This review summarizes studies highlighting perfluoroalkyl substances (PFAS) and their effects on the placenta, pregnancy outcomes, and child health. It highlights human population-based associations as well as in vitro-based experimental data to ...

2025年3月1日 · Animal studies have linked prenatal poly- and perfluoroalkyl substances (PFAS) exposures with impaired placental structure and function. In humans, only few studies have investigated such associations. We studied whether PFAS, individually and as a mixture, affected placental function.

1 天前 · Polyfluoroalkyl and perfluoroalkyl substances (PFAS) are persistent organic pollutants and exposure have been suggested with the risk of developing preeclampsia. Yet, evidence on the associations of PFAS with preeclampsia is still conflicting. Thus, the current study conducted a systematic review and meta-analysis of the epidemiological evidence linking maternal PFAS exposure to preeclampsia ...

2024年7月25日 · Cohorts of pregnant women in 2018 and 2020 were selected to explore prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances (PFAS). Maternal serum during the whole pregnancy (first to third trimesters) and matched cord …

2025年3月1日 · For pregnant patients, health effects include gestational hypertension and preeclampsia. Some of these chemicals can pass through human breastmilk and when tested, are routinely found in umbilical cord blood and fetal organs (ATSDR, 2021). ... PFAS levels exceed EPA's Lifetime Health Advisory (LTHA) in drinking water in most states. An overview ...

2024年12月1日 · Increasing evidence has linked prenatal PFAS exposure to adverse pregnancy outcomes, including preeclampsia, altered birthweight, and preterm birth, with potential long-term implications for postnatal development (Gao et al., 2021).

We found that PFAS exposure during pregnancy impacts both maternal and child health. Future studies are needed to determine the impact on child growth and development and to investigate potential interventions to limit the impact of PFAS exposure during pregnancy.[¤]

Recent findings: In utero exposure to prevalent environmental contaminants such as PFAS is associated with negative health outcomes during pregnancy, birth outcomes, and later in life. Specifically, PFAS have been associated with increased incidence of gestational diabetes, childhood obesity, preeclampsia, and fetal growth restriction.

2025年3月6日 · All PFAS had a quantification rate above 75% in maternal pregnancy serum besides PFPeS, which had a quantification rate of 35%. PFAS levels were generally lower in cord serum compared with ...

2024年10月8日 · Over the past decade, the harmful effects of PFAS on human health have become increasingly clear with pregnant women and children especially at risk. In this blog, we present an overview of the latest science on health outcomes for mothers and children linked to PFAS exposure during pregnancy.