Prostaglandin D2 (or PGD2) is a prostaglandin that binds to the receptor PTGDR (DP 1), as well as CRTH2 (DP 2). [1][2] It is a major prostaglandin produced by mast cells – recruits Th2 cells, eosinophils, and basophils. In mammalian organs, large amounts of PGD 2 are found only in the brain and in mast cells.

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The prostaglandin D2 (PGD2) receptors are G protein-coupled receptors that bind and are activated by prostaglandin D 2. [1][2] Also known as PTGDR or DP receptors, they are important for various functions of the nervous system and inflammation. They include the following proteins:

Prostaglandin D2 is a member of the class of prostaglandins D that is prosta-5,13-dien-1-oic acid substituted by hydroxy groups at positions 9 and 15 and an oxo group at position 11 (the 5Z,9alpha,13E,15S- stereoisomer). It has a role as a human metabolite and a mouse metabolite. It is a conjugate acid of a prostaglandin D2 (1-).

2021年10月22日 · PGD 2 stimulates three distinct types of G protein-coupled receptors: (1) D type of prostanoid (DP) receptors involved in the regulation of sleep, pain, food intake, and others; (2) chemoattractant receptor-homologous molecule expressed on T helper type 2 cells (CRTH2) receptors, in myelination of peripheral nervous system, adipocyte differentia...

2024年7月25日 · Increased production of Prostaglandin D 2 (PGD 2) is linked to development and progression of asthma and allergy. PGD 2 is rapidly degraded to its metabolites, which initiate type 2 innate lymphoid cells (ILC2) migration and IL-5/IL-13 cytokine secretion in a PGD 2 receptor 2 (DP 2)-dependent manner.

2024年12月25日 · The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system.

Prostaglandin D 2 (PGD 2) is the most profuse PGD in the CNS of mammals. It is generated by lipocalin-type PGD (L-PGD) synthase which is found mainly in the leptomeninges, choroid plexus and oligodendrocytes, and discharged in the cerebrospinal fluid as a somnogen.

LD 的电子头与测桿的内连接线是一个 240 mm 的固定长度，而 LD2 的电子头与测桿的内连接线则有 3 个固定长度可选，即 140 mm、200 mm 和 320 mm。 用户可以把线长缩短以符合实际需要(注意 : 如果用户擅自把内接线加长的话，则 MTS提供的 12 个月保修期马上失效)。

2023年3月4日 · I think it is a time to add LD2 support to GoldenDict for PC as well. Just in case, there are multiple open implementations for the LD2 file format: - https://code.google.com/p/lingoes-extractor/ - https://github.com/windylea/lingoes-converter - https://code.google.com/p/dict4cn/source/browse/trunk/importer/src/LingoesLd2Reader.java