Polyhexanide (polyhexamethylene biguanide, PHMB) is a polymer used as a disinfectant and antiseptic. In dermatological use, [4] it is spelled polihexanide and sold under various brand names. [5]

Jul 13, 2017 · According to Winard, PHMB is a "synthetic polymer that is used as a broad-spectrum preservative and antimicrobial agent in skin care." Drs. Shetler and Falsetti add that it can be found in...

Our AMD antimicrobial dressings contain PHMB (polyhexamethylene biguanide), a bacteria-killing polymer. PHMB attacks bacteria on and within the dressing fabric, helping keep infection out of the wound and limiting cross-contamination.

Here we examined how the widely used antimicrobial polyhexamethylene biguanide (PHMB) kills bacteria selectively over host cells.

Jun 4, 2020 · Polyhexamethylene biguanide (PHMB) is a cationic polymer with antimicrobial and antiviral properties. It has been commonly accepted that the antimicrobial activity is due to the ability of PHMB to perforate the bacterial phospholipid membrane leading ultimately to its death.

PHMB, belonging to the biguanide class, boasts a polymeric structure that imparts exceptional antimicrobial capabilities. This article explores PHMB’s chemical intricacies, applications, and scientific foundations supporting its efficacy as a disinfectant.

Learn about PHMB, its health risks and how to reduce your exposure. Poly (hexamethylenebiguanide), or PHMB, may also be called: PHMB does not occur naturally in the environment. It's found in a wide range of products available to consumers. For example, it's used as an antimicrobial agent or preservative in:

Jun 13, 2019 · According to Winard, PHMB is a "synthetic polymer that is used as a broad-spectrum preservative and antimicrobial agent in skin care." Drs. Shetler and Falsetti add that it can be found in many personal-care products "including skin care, cosmetics, eye-care solutions, wound care, and surgery care."

Sep 9, 2022 · Polyhexamethylene biguanide hydrochloride (Polyhexanide, PHMB) is a broad-spectrum antiseptic with excellent tolerance and a low-risk profile. Its physicochemical action on the phospholipid membrane and DNA replication or repair mechanism, prevents or impedes the development of resistant bacterial strains.

Mar 14, 2025 · Explore how PHMB antimicrobial interacts at the cellular level, from membrane disruption to nucleic acid binding, and methods for studying its effects. Polyhexamethylene biguanide (PHMB) is a broad-spectrum antimicrobial widely used in medical, industrial, and consumer applications.