2021年10月20日 · Compounded topical pain creams offer some promising options for PHN treatment as well, yet evidence supporting their use remains limited. Although available studies indicate that topical therapies may provide some pain relief when administered alone, it appears that maximum benefit is achieved when topical agents are used in combination with ...

2020年3月16日 · Membrane stabilizers: Medications such as gabapentin can be used to reduce the pain associated with PHN. Capsaicin cream: This topical cream can be applied to the affected area to relieve pain temporarily. Patients with refractory PHN rarely need opioid (narcotic) pain medication. “However, you should be evaluated by a physician.

2023年2月10日 · An over-the-counter medicine called capsaicin cream may ease the pain of postherpetic neuralgia. It's made from the seeds of hot chili peppers. Capsaicin (Capzasin-P, Zostrix, others) can cause a burning feeling and may bother your skin.

Our meta-analysis displayed 6 topical drugs for PHN. Lidocaine, high-concentration capsaicin, and aspirin/diethyl ether (ADE) had a higher possibility of bringing pain relief than placebo.

2022年4月12日 · Topical treatments like creams, ointments, and lotions can help you manage irritation and itchiness. They may also help manage lingering nerve pain called postherpetic neuralgia (PHN). Some...

Because PHN is a localized condition, localized therapy with a topical analgesic (lidocaine patch 5% and capsaicin 8% patch or cream) may provide adequate efficacy while mitigating the risk of systemic adverse events compared with oral analgesics (eg, tricyclic antidepressants, anticonvulsants, opioids).

The analgesic efficacy of 5% of EMLA cream (5 or 10 g) when applied for 24 h periods was evaluated in 5 female and 7 male patients (mean age 69 years, range 50-85 years) with refractory post-herpetic neuralgia (PHN). Mean visual analogue pain intensity scores for all patients were significantly impr …

2021年6月22日 · Being vaccinated against shingles is the best way to prevent postherpetic neuralgia (PHN), lingering pain from the shingles virus. Here's what you should know about the causes, symptoms, and...

PHN is likely to interfere with sleep and daily activities. First-line therapies for PHN include tricyclic antidepressants, gabapentin and pregabalin, and the lidocaine 5 % patch. Second-line therapies include strong and weak opioids and topical capsaicin cream or 8 % patch.

For the initial treatment of PHN, the recommended first- and second-line agents are gabapentin, a lidocaine patch, opioid analgesics, and tricyclic antidepressants (Dworkin et al., 2003). Like the cream formulation, capsaicin patches may cause a burning sensation (Das et al., 2013).