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2024年12月25日 · PI 3-Kinases (phosphoinositide 3-kinases, PI 3-Ks) are a family of lipid kinases capable of phosphorylating the 3'OH of the inositol ring of phosphoinositides. They are …

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磷脂酰肌醇3-激酶 (PI3Ks)蛋白家族参与细胞存活、生长、代谢和血糖稳态等多种细胞功能的调控。 PI3K激酶活性升高通常与多种癌症相关。顾名思义，PI3Ks磷酸化磷脂酰肌醇PI（一种膜磷 …

The PIK-3 (Polyteknikkojen Ilmailukerho – Finnish institute of technology students flying club) was a sailplane produced in Finland in the 1950s and 60s. [1] . It was designed to be a cheap and …

The PIK3CA gene provides instructions for making the p110 alpha (p110α) protein, which is one piece (subunit) of an enzyme called phosphatidylinositol 3-kinase (PI3K). The p110α protein is …

PI3K是一种胞内磷脂酰肌醇激酶，与v．src和v．ras等癌基因的产物相关，且PI3K本身具有丝氨酸/苏氨酸 (Ser/Thr)激酶的活性，也具有磷脂酰肌醇激酶的活性。 由调节亚基p85和催化亚 …

磷酸肌醇 3-激酶 (PI3K) 和磷酸肌醇 3-激酶相关蛋白激酶 (PIKK) 是两个结构相关的激酶家族，在细胞生长和 DNA 损伤修复中发挥重要作用。 PIKK 成员的功能障碍和 PI3K/AKT/mTOR 信号通 …