2012年9月27日 · TP53 encodes the multi-functional tumor suppressor transcription factor p53 which has a crucial role in maintaining genomic stability in somatic cells exposed to oncogenic …

2014年9月15日 · A single mutation of the allele with PIN3 duplication in PIN3 heterozygotes (A1/A2) might be partially responsible for TP53 haploinsufficiency. These findings may provide …

TP53 encodes the multi-functional tumor suppressor tran-scription factor p53 which has a crucial role in maintaining genomic stability in somatic cells exposed to...

2013年2月14日 · We have performed a meta-analysis of cancer risk associated with the rs17878362 polymorphism of the TP53 suppressor gene (PIN3, (polymorphism in intron 3), 16 …

2012年9月27日 · p53 has a crucial role in human fertility by regulating the expression of leukemia inhibitory factor (LIF), a secreted cytokine critical for blastocyst implantation. To examine …

Our results indicate that the TP53 PIN3 polymorphism has a sex-specific effect on the risk of cancer in TP53 mutation carriers, conferring cancer risk in men ( P = 0.0041) but not women …

2014年9月15日 · We hypothesized that different TP53 gene expression levels of each allele may be caused by the polymorphism within intron 3 (PIN3). The aim of this study was to test if one …

The present study aimed to assess the association of PIN3 Ins16bp polymorphism of p53 with breast cancer risk in Moroccan population. This case-control study was performed on 105 …

2012年9月27日 · TP53 encodes the multi-functional tumor suppressor transcription factor p53 which has a crucial role in maintaining genomic stability in somatic cells exposed to oncogenic …

2012年9月1日 · TP53 polymorphisms and haplotypes were identified by amplification refractory mutation system polymerase chain reaction. TP53 PIN3 and PEX4 were associated with both …