
Plectin in Health and Disease - PMC - PubMed Central (PMC)
Based on plectin’s broad interaction potential, strategic locations, and ample functional repertoire, dysfunctional plectin leads to a variety of disorders and diseases.
Plectin: Current Biology - Cell Press
2023年2月27日 · What is plectin? Plectin is a giant cytoskeletal crosslinker (also known as a cytolinker) protein of more than 4,500 amino acids. It belongs to the plakin family of giant …
PLEC Gene - GeneCards | PLEC Protein | PLEC Antibody
2024年12月25日 · Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking …
Plectin in Cancer: From Biomarker to Therapeutic Target - PMC
The cytolinker and scaffolding protein, plectin, has emerged as a potent driver of malignant hallmarks in many human cancers due to its involvement in various cellular activities …
Mechanics of cell sheets: plectin as an integrator of cytoskeletal ...
2025年1月29日 · Finally, as increasing evidence suggests that plectin can regulate signalling pathways in response to mechanical cues, we propose a concept in which plectin represents a …
Role of plectin and its interacting molecules in cancer
2023年8月26日 · Herein, we summarized the structure, expression and function of plectin, and mainly focused on recent studies on the functional and physical interactions between plectin …
Plectin ensures intestinal epithelial integrity and protects …
2021年3月5日 · Plectin, a highly versatile cytolinker protein, provides tissues with mechanical stability through the integration of intermediate filaments (IFs) with cell junctions.
Plectin: Dual Participation in Tumor Progression - MDPI
2024年8月24日 · Here, we first introduce the molecular structure and function of plectin, and then we summarize the current understanding of the crucial role of plectin in cancer progression.
Plectin - an overview | ScienceDirect Topics
Plectin, encoded by PLEC, is a highly conserved and ubiquitously expressed intermediate filament-linking protein with tissue and organelle-specific transcript isoforms that serves as a …
Plectin ensures intestinal epithelial integrity and protects colon ...
2021年3月5日 · Plectin, a highly versatile cytolinker protein, provides tissues with mechanical stability through the integration of intermediate filaments (IFs) with cell junctions. Here, we …
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