PLPP3 Gene - GeneCards | PLPP3 Protein | PLPP3 Antibody
2024年12月25日 · PLPP3 (Phospholipid Phosphatase 3) is a Protein Coding gene. Diseases associated with PLPP3 include Sigmoid Disease and Congenital Generalized Lipodystrophy. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway. An important paralog of this gene is PLPP1.
8613 - Gene ResultPLPP3 phospholipid phosphatase 3 [ (human)]
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D.
磷脂磷酸酶 3（PLPP3）基因 | MCE
The protein encoded by this gene is a member of the phosphatidic Acid Phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by Phospholipase D.
Regulation of PLPP3 gene expression by NF-κB family …
2019年9月20日 · Lipid phosphate phosphatase 3 (LPP3), encoded by the PLPP3 gene, is an integral membrane enzyme that dephosphorylates phosphate esters of glycero- and sphingophospholipids. Cell surface LPP3 can terminate the signaling actions of bioactive lysophosphatidic acid (LPA) and sphingosine 1 phosphate, whi …
PLPP3 phospholipid phosphatase 3 [Homo sapiens (human)] - Gene …
The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D.
Liver-specific deletion of the Plpp3 gene alters plasma lipid ...
2017年3月14日 · The PLPP3 gene encodes for a ubiquitous enzyme that dephosphorylates several lipid substrates. Genome-wide association studies identified PLPP3 as a gene that plays a role in coronary artery...
PLPP3 (human) | Gene Target - PubChem
2016年9月14日 · The protein encoded by the PLPP3 gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D.
PLPP3 phospholipid phosphatase 3 - NIH Genetic Testing …
2025年2月8日 · The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D.
Coronary Artery Disease Risk-Associated Plpp3 Gene and Its …
2019年9月19日 · PLPP3 encodes LPP3 (lipid phosphate phosphatase 3), a cell-surface enzyme that can regulate the availability of bioactive lysophopsholipids including lysophosphatidic acid (LPA). The protective allele of PLPP3 increases LPP3 expression during cell exposure to oxidized lipids, however, the role of LPP3 in atherosclerosis remains unclear.
The coronary artery disease risk-associated Plpp3 gene and its …
Lipid phosphate phosphatase 3 (LPP3), encoded by the gene PLPP3, is a cell surface enzyme that can regulate the availability and hence the signaling actions of bioactive lipids including lysophosphatidic acid (LPA). The risk-associated haplotype block is in the final intron of PLPP3 and contains a CCAAT enhancer binding protein beta (CEBPβ) motif.