2025年1月31日 · Chest radiographs may appear normal, however certain signs of pulmonary hypertension may be present, such as 4,6: Echocargiography is the gold standard to confirm the diagnosis of PPHN. It also the best modality to monitor treatment efficacy. Important measurements include 4:

Persistent pulmonary hypertension of the newborn, or PPHN, is a life-threatening breathing issue that occurs when your newborn doesn’t adapt to breathing outside of your uterus. PPHN happens when your baby’s pulmonary arteries don’t open up enough, so your baby’s brain and organs don’t get enough oxygen.

Aims: To compare echocardiographic (ECHO) measures of ventricular function and hemodynamics of infants with persistent pulmonary hypertension of the newborn (PPHN) and normal controls; and to examine their association with clinical outcomes in PPHN.

2023年7月31日 · Persistent pulmonary hypertension of the newborn is a life-threatening condition in the immediate neonatal period. It may be due to lung parenchymal disease such as respiratory distress syndrome or due to underdeveloped lung vasculature in conditions such as congenital diaphragmatic hernia and small for gestational age infants.

2018年8月2日 · Persistent pulmonary hypertension of the newborn (PPHN) is a complex disorder that is characterized by the presence of an increased pulmonary vascular resistance (PVR)...

Two-dimensional (2D) echocardiography provides qualitative and quantitative evaluation of the severity of PH. The right atrium (RA) dilates over time in patients with PH and it represents decreased right ventricular (RV) compliance and RV diastolic dysfunction.

Persistent pulmonary hypertension of the newborn (PPHN) is a syndrome of failed circulatory adaptation at birth due to delay or impairment in the normal fall in pulmonary vascular resistance (PVR) that occurs following birth. The fetus is in a state of physiological pulmonary hypertension.

Understanding the pathophysiology is of paramount importance in diagnosis and management of persistent pulmonary hypertension of the newborn (PPHN). Echocardiography is diagnostic in PPHN – for confirming diagnosis, assessing the severity, understanding pathophysiology, guiding targeted specific therapy and monitoring response to therapy.

2024年3月12日 · In PPHN, elevated pulmonary artery pressure (PAP) is usually secondary to elevated PVR and has the following etiologies: (1) maladaptation: the structure and number of pulmonary vessels are normal but vasoreactivity of them is abnormal; (2) maldevelopment: increased smooth muscle cell thickness and increased distal extension of muscle to vessels...

2023年8月1日 · Echocardiography (ECHO) remains an important tool for the evaluation and management of patients with PPHN. ECHO is used to rule out congenital heart disease, evaluate heart function and to look for evidence of increased pulmonary arterial pressure.