
Pollution Removal Funding Authorizations (PRFAs) - United …
Download and complete this form to establish a PRFA with a state or local government. Download and complete this form to amend an existing PRFA with either a federal or non-federal …
Aug 15, 2017 · The Pollution Removal Funding Authorization (PRFA) is a tool available to FOSCs to quickly obtain needed services and assistance from other government agencies: federal, …
After award of the PRFA, the Department bureaus and offices should coordinate with their budget and accounting personnel and follow their internal procedures in creating a new reimbursable …
Regulation of Listeria virulence: PrfA master and commander
Apr 1, 2011 · PrfA, a regulatory protein, integrates a number of environmental cues that signal the transition between these two contrasting lifestyles, activating a set of key virulence factors …
Structural basis of promiscuous inhibition of Listeria virulence ...
Feb 25, 2025 · Hainzl et al. structurally explain the mechanism of promiscuous (sequence-independent) inhibition of Listeria virulence activator PrfA by environmental oligopeptides. …
The PrfA virulence regulon - ScienceDirect
Aug 1, 2007 · PrfA integrates a number of environmental and bacteria-derived signals to ensure the correct spatio-termporal and niche-adapted expression of the regulon, with maximum …
A Tale of Two Transitions: The Unfolding Mechanism of the prfA …
Dec 8, 2020 · PrfA functions as a master regulator of virulence in L. monocytogenes, controlling the expression of many virulence factors. The temperature-regulated expression of PrfA by its …
PrfA regulation offsets the cost of L isteria virulence outside the ...
Aug 27, 2015 · Using a mutant PrfA regulator locked ON (PrfA *) and thus causing PrfA ‐controlled genes to be constitutively activated, we show that virulence gene expression …
PrfA, the transcriptional activator of virulence genes, is …
Most virulence genes of Listeria monocytogenes are activated by the transcriptional regulator PrfA. Previous studies have shown that environmental parameters, such as temperature, pH, …
Targeting PrfA from Listeria monocytogenes: A computational …
Dec 1, 2024 · PrfA is considered the main regulator of L. monocytogenes’ virulence and its role in bacterial propagation inside the host is well-documented (Freitag et al., 1993, Chakraborty et …