
PSAT1 Gene - GeneCards | SERC Protein | SERC Antibody
2024年12月25日 · PSAT1 (Phosphoserine Aminotransferase 1) is a Protein Coding gene. Diseases associated with PSAT1 include Neu-Laxova Syndrome 2 and Phosphoserine …
PSAT1 - Wikipedia
Phosphoserine aminotransferase (PSA) also known as phosphohydroxythreonine aminotransferase (PSAT) is an enzyme that in humans is encoded by the PSAT1 gene. [5] …
Targeting PSAT1 to mitigate metastasis in tumors with p53
2023年2月15日 · Our finding revealed a non-enzymatic role of PSAT1, in which PSAT1 might be essential for metabolic rerouting during tumor cell metastasis, and targeting PSAT1 may hold …
PSAT1 phosphoserine aminotransferase 1 [ (human)] - National …
2025年2月9日 · PSAT1 promotes autophagy to resist insufficient autophagy caused by cigarette smoke extract in human airway epithelial cells. Overexpression of PSAT1 is Correlated with …
The unique catalytic properties of PSAT1 mediate metabolic
2024年8月27日 · Mechanistically, we find that phosphoserine aminotransferase 1 (PSAT1) has a unique capacity for sustained α-KG production when glutamate is depleted. Breast cancer …
Phosphoserine Aminotransferase 1: A Metabolic Enzyme Target of …
Phosphoserine aminotransferase 1 (PSAT1) catalyzes 3-phosphohydroxylpyruvate and glutamate into 3-phosphoserine and α-ketoglutamate. It integrates metabolic pathways critical for cell …
Interplay between acetylation and ubiquitination controls PSAT1 …
2024年10月21日 · Phosphoserine aminotransferase 1 (PSAT1) is a key enzyme in de novo serine synthesis. However, little is known about the mechanisms underlying PSAT1 degradation. We …
PSAT1 is regulated by ATF4 and enhances cell proliferation via the ...
PSAT1 is the protein-coding gene of phosphoserine aminotransferase, which catalyzes serine biosynthesis. PSAT1 is overexpressed in colon cancers where it contributes to cell …
PSAT1 is regulated by ATF4 and enhances cell proliferation via the ...
2017年12月8日 · Background: A growing amount of evidence has indicated that PSAT1 is an oncogene that plays an important role in cancer progression and metastasis. In this study, we …
PSAT1 Regulated Oxidation-Reduction Balance Affects the …
2020年6月11日 · Down-regulation of PSAT1 inhibits the clonogenicity, cell cycle and promotes apoptosis. PSAT1 expression increases the proportion of GSH and reduced nicotinamide …