2016年10月3日 · The concept of pyrexia as a protective physiological response to aid in host defence has been challenged with the awareness of the severe metabolic stress induced by pyrexia. The host response to pyrexia varies, however, according to the disease profile and severity and, as such, the management of pyrexia should differ; for example, temperature …

2016年9月1日 · Most episodes of pyrexia are due to infections, but incidence estimates of infectious and noninfectious aetiologies are limited by studies with small sample size and inconsistent reporting of noninfectious aetiologies. Pyrexia commonly triggers a full septic work-up, but on its own is a poor predictor of culture-positivity.

2016年7月14日 · The teleological benefit of pyrexia following brain injury is uncertain. Endocrine fever. Thyroid hormones are essential for regulation of energy metabolism. Hyperthyroidism is associated with hyperthermia; patients with thyroid storm have an average body temperature of 38.0 °C; temperatures above 41 °C have been reported . The mechanism of ...

2014年2月13日 · Changes in body temperature are a characteristic feature of sepsis. The study by Kushimoto and colleagues in a recent issue of Critical Care demonstrates that hypothermia is a very important manifestation of infection associated with very high mortality. Combined with recent data suggesting that febrile patients with infections have the lowest mortality risk, the study …

noninfectious pyrexia, is more commonly observed in patients with hyperthermia. Most episodes of pyrexia are due to infections, but incidence estimates of infectious and noninfectious aetiologies are limited by studies with small sample size and inconsistent reporting of noninfectious aetiologies. Pyrexia commonly triggers a full septic work-up,

2015年4月12日 · meaning simply ‘heat’, and pyrexia comes from the Greek ‘pyr’, meaning fire or fever. Some sources use the terms interchangeably, whereas others preserve ‘fever’ to mean a raised temperature caused by the action of thermoregula-tory pyrogens on the hypothalamus; for instance, in sepsis and inflammatory conditions [3].

The cost of pyrexia should be considered in several ways. Pyrexia has a metabolic cost such that cooling fe-brile ICU patients will reduce oxygen consumption by 10 % per °C [6]. Small studies in sedated patients dem-onstrated a significant reduction in VO 2 (the rate of oxy-gen consumption) and VCO 2 (the rate of carbon dioxide

2014年10月14日 · Introduction Temperature changes are common in patients in a neurosurgical intensive care unit (NICU): fever is frequent among severe cases and hypothermia is used after cardiac arrest and is currently being tested in clinical trials to lower intracranial pressure (ICP). This study investigated cerebral hemodynamics when body temperature varies in acute brain …

2011年6月7日 · In recent years, fever control in critically ill patients by medications and/or external cooling has gained widespread use, notably in patients suffering from neurological injuries. Nevertheless, such a strategy in septic patients is not supported by relevant data. Indeed, in response to sepsis, experimental and clinical studies argue that fever plays a key role in …

2022年11月24日 · Most of the patients who die after cardiac arrest do so because of hypoxic-ischemic brain injury (HIBI). Experimental evidence shows that temperature control targeted at hypothermia mitigates HIBI. In 2002, one randomized trial and one quasi-randomized trial showed that temperature control targeted at 32–34 °C improved neurological outcome and mortality in …