In this review, we discuss advances in quantitative phase imaging (QPI), a label-free microscopy technique that measures fundamental cell properties and behaviors, including mass, mechanical properties, growth, and intracellular transport.

2018年9月27日 · Quantitative phase imaging (QPI) has emerged as a valuable method for investigating cells and tissues. QPI operates on unlabelled specimens and, as such, is...

2018年10月19日 · Quantitative phase imaging (QPI) is an emerging label-free modality that attracts significant interest in biomedicine in general and neuroscience in particular. Based on the principle of interferometry, QPI precisely maps the optical pathlength induced by the sample, and, thus, can visualize extremely transparent samples.

In this study, we proposed a novel approach to QPI using the combined ssQPGI module (Figure 1) and the LAR algorithm (Figure 2), and we demonstrated some application examples (Figures 5-8 and S2–S4, Videos S1-S4). The optical configuration has advantages for cell biology applications from the following four perspectives.

Quantitative phase imaging (QPI) is a label-free technique that provides optical path length information for transparent specimens, finding utility in biology, materials science, and engineering. Here, we present QPI of a three-dimensional (3D) stack of phase-only objects using a wavelength-multiplexed diffractive optical processor.

Comparison of the measured QPI spectra with theory a,b, Experimental QPI images g (q, V) obtained at zero bias on the p = 0.10 surface above (a) and below Tc (b). c,d, Simulated QPI images...

QPI patterns on various surfaces of CoSi. (A and B) FFT images transformed from the dI/dV maps taken on the (001) surface over an area of 25 nm by 21 nm at 0 and +20 mV. U = +60 mV, I = 200 pA;...

Phasics introduces a new modality in light microscopy: Quantitative Phase Imaging. Phasics's innovative technique relies on a camera-like instrument and enables easy label-free imaging of specimens such as live cells, tissues, or any other semi-transparent samples.

QPI is a 3D-IC semiconductor device comprising a high density array of digitally addressable micro-size pixels [5]. Each pixel (see Figure 1) consists of a vertical stack of multiple Light...

2013年4月25日 · Quantitative phase imaging (QPI) is emerging as a highly sensitive, real-time method for basic science and clinical applications. It can be used to measure nanometer-scale path length changes induced by a transparent specimen.