璩 良 - Fudan University
4. Chunsheng Dong*#, Liang Qu*, Haoyi Wang, Lin Wei, Yuanshu Dong, Sidong Xiong#. Targeting hepatitis B virus cccDNA by CRISPR/Cas9 nuclease efficiently inhibits viral replication. Antiviral...
Liang QU (曲良)
I am a third-year data science Ph.D. student jointly supervised by The University of Queensland (UQ) and Southern University of Science and Technology (SUSTech), advised by Prof. Yuhui Shi and Prof. Hongzhi Yin.
Liang QU - Google Scholar
Proceedings of the 33rd ACM International Conference on Information and …
魏文胜实验室
主要从事生物信息学的应用研究，多年深耕于生物信息学，从基因芯片到二代测序、三代测序，从基因组、转录组、单细胞转录组、表观组到蛋白代谢等，致力于通过生物信息学手段解析生命与疾病背后复杂的生物学机制。 已发表文章请参阅ORCID个人主页: https://orcid.org/0000 …
Programmable RNA editing by recruiting endogenous ADAR using …
2019年7月15日 · We show that arRNA, delivered by a plasmid or viral vector or as a synthetic oligonucleotide, achieves editing efficiencies of up to 80%. LEAPER is highly specific, with rare global off-targets and...
Liangliang Qu - Google Scholar
Effect of filler–elastomer interactions on the mechanical and nonlinear viscoelastic behaviors of chemically modified silica‐reinforced solution‐polymerized styrene butadiene … WZ Luoran Shang,...
Circular RNA vaccines against SARS-CoV-2 and emerging variants
2022年5月12日 · Here, we report a circular RNA (circRNA) vaccine that elicited potent neutralizing antibodies and T cell responses by expressing the trimeric RBD of the spike protein, providing robust protection against SARS-CoV-2 in both mice and rhesus macaques.
QU Liang-管理与经济学部
2021年6月10日 · Time Company Position; Nov,2013-Now: School of management, Tianjin University: Assistant Professor: Apr,2013- Sep,2013: Department of Industry Engineering, The State University of New Jersey
复旦大学璩良团队利用circRNA体内表达CAR和肿瘤抗原协同促进抗 …
2024年7月23日 · 该研究表明，基于circRNA体内表达CAR与肿瘤抗原 (称为体内CAR- VAC)的结合，有可能成为一种升级的成品免疫疗法。 CircRNACAR可在T细胞和巨噬细胞中有效表达CAR蛋白. 研究团队对HER2 CAR序列进行密码子优化后，采用I型内含子自剪接策略合成表达HER2 CAR蛋白的circRNA（circRNACAR），采用HPLC和RNase R处理得到高纯度circRNACAR，将circRNACAR转染到细胞中，通过Western Blot验证CAR蛋白的表达，选出表达最高效 …
Liang QU | Principal Investigator | Ph.D - ResearchGate
Liang Qu currently works at the Biologics, BeiGene. Liang does research in Molecular Biology, Biotechnology and Immunology. Their most recent publication is 'High Throughput Identification...