
About Mutations in the RAD51C Gene - Memorial Sloan Kettering Cancer Center
2023年7月17日 · A RAD51C mutation increases your risk for ovarian cancer. A RAD51C mutation may also increase your risk for breast cancer, but more research is needed for us to better …
RAD51C - Wikipedia
The RAD51C gene is one of genes four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during …
RAD51C Gene - GeneCards | RA51C Protein | RA51C Antibody
2024年12月25日 · RAD51C (RAD51 Paralog C) is a Protein Coding gene. Diseases associated with RAD51C include Breast-Ovarian Cancer, Familial 3 and Fanconi Anemia, …
实力靶点RAD51:损伤修复,不辨不明 - 知乎 - 知乎专栏
基于DNA损伤修复原理在PARP上取得的成功以及PARP抑制剂耐药的出现,一些相关靶点RAD51、Wee1、ATM、ATR、PRMT5等也引起了研发人员的极大热情,成为近年来的热门 …
Cancer Risk in People with a RAD51C Mutation
2024年9月22日 · Women with a RAD51C mutation have about a 10-15 percent lifetime risk for ovarian, fallopian tube or primary peritoneal cancer (these three cancers and their risks are …
High-resolution functional mapping of RAD51C by saturation …
2024年9月18日 · Pathogenic variants in RAD51C confer an elevated risk of breast and ovarian cancer, while individuals homozygous for specific RAD51C alleles may develop Fanconi …
RAD51C-XRCC3 structure and cancer patient mutations define …
2023年7月24日 · Here we report the RAD51C-XRCC3 (CX3) X-ray co-crystal structure with bound ATP analog and define separable RAD51C replication stability roles informed by its three …
RAD51C RAD51 paralog C [ (human)] - National Center for …
RAD51C and RAD51D are moderate ovarian cancer susceptibility genes. RAD51C mutation is associated with breast and ovarian cancer. The effect of common single nucleotide …
Abnormal expression of Rad51C, which is a key factor in the HR pathway, may result in DNA repair disorder, genomic instability, and eventually lead to tumor formation. In recent studies, …
What is my cancer risk if I have a RAD51C mutation? A RAD51C mutation increases your risk for ovarian cancer. A RAD51C mutation may also increase your risk for breast cancer, but more …