2023年7月17日 · A RAD51C mutation increases your risk for ovarian cancer. A RAD51C mutation may also increase your risk for breast cancer, but more research is needed for us to better …

The RAD51C gene is one of genes four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during …

2024年12月25日 · RAD51C (RAD51 Paralog C) is a Protein Coding gene. Diseases associated with RAD51C include Breast-Ovarian Cancer, Familial 3 and Fanconi Anemia, …

基于DNA损伤修复原理在PARP上取得的成功以及PARP抑制剂耐药的出现，一些相关靶点RAD51、Wee1、ATM、ATR、PRMT5等也引起了研发人员的极大热情，成为近年来的热门 …

2024年9月22日 · Women with a RAD51C mutation have about a 10-15 percent lifetime risk for ovarian, fallopian tube or primary peritoneal cancer (these three cancers and their risks are …

2024年9月18日 · Pathogenic variants in RAD51C confer an elevated risk of breast and ovarian cancer, while individuals homozygous for specific RAD51C alleles may develop Fanconi …

2023年7月24日 · Here we report the RAD51C-XRCC3 (CX3) X-ray co-crystal structure with bound ATP analog and define separable RAD51C replication stability roles informed by its three …

RAD51C and RAD51D are moderate ovarian cancer susceptibility genes. RAD51C mutation is associated with breast and ovarian cancer. The effect of common single nucleotide …

Abnormal expression of Rad51C, which is a key factor in the HR pathway, may result in DNA repair disorder, genomic instability, and eventually lead to tumor formation. In recent studies, …

What is my cancer risk if I have a RAD51C mutation? A RAD51C mutation increases your risk for ovarian cancer. A RAD51C mutation may also increase your risk for breast cancer, but more …