2022年8月6日 · 肾细胞癌（RCC）的分类主要基于肿瘤的细胞学和结构特征以及免疫组化表达谱。 目前的世界卫生组织（WHO）分类由14个亚型RCC组成。 近年来，世界卫生组织认可的实体数量有所增加，并且随着新的或“新兴”亚型被考虑纳入而继续发展。 在本章中，我们概述了RCC不同亚型的关键特征，包括与遗传综合征相关的特征。 我们描述了未来可能被正式认可的2种“新兴”实体的特征，并简要讨论了新型生物标志物在RCC中的作用。 在过去25年中，肾脏恶性上皮肿瘤 …

发病率超过5%的主要肾癌（ renal cell carcinoma，RCC）亚型包括：透明细胞RCC (clear cell RCC，ccRCC) 、乳头状RCC (papillary RCC，pRCC) 和嫌色RCC (chromo phobe RCC，chRCC) 。

2024年2月15日 · Clear cell renal cell carcinoma (ccRCC) is a complex disease with remarkable immune and metabolic heterogeneity. Here we perform genomic, transcriptomic,...

Clear cell renal cell carcinoma, or ccRCC, is a type of kidney cancer. The kidneys are located on either side of the spine towards the lower back. The kidneys work by cleaning out waste products in the blood. Clear cell renal cell carcinoma is also called conventional renal cell carcinoma.

2024年1月7日 · Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer. It affects the tubules that filter waste from your blood. The cancer cells look like clear bubbles under a microscope. Treatment commonly involves surgery to remove the tumor or your entire kidney. But you may also need other treatments.

目前批准用于转移性透明细胞性肾细胞癌（ccrcc）的靶向药物有6大类13个药品，分别为vegfr、mtorc1、c-met和fgfr抑制剂、细胞因子和抗pd1/pdl1免疫检查点抑制剂 [1] 。在过去的10年中，这些药物成功将转移性ccrcc患者的中位生存期从15个月增加到30个月 [1] 。然而不同 ...

Renal cell carcinoma (RCC) is a heterogeneous group of cancers arising from renal tubular epithelial cells that encompasses 85% of all primary renal neoplasms 1, 2. The most common subtypes of RCC are clear cell RCC (ccRCC), papillary RCC, and chromophobe RCC 1. The remaining 15% of tumors of the kidney consist of transitional cell carcinoma (8 ...

21 小时之前 · Of all RCC cases, clear cell RCC (ccRCC) is the top prevalent, making up about 80% of adult cases. In the early stages of ccRCC, patients typically undergo par tial nephrectomy, where only the affected portion of the kidney is removed. However, for centrally located tumors or larger growths, a radical nephrectomy (full kidney removal) might be ...

2025年3月17日 · Renal cell carcinoma (RCC) constitutes 85% of kidney cancer and consists of 3 major subtypes: clear cell RCC (ccRCC, 80%), papillary RCC (pRCC, 15%), and chromophobe RCC (chRCC, 5%) . ccRCC is the ...

Renal clear cell carcinoma (ccRCC) comprises over 75% of all renal tumors and arises in the epithelial cells of the proximal convoluted tubule. Molecularly ccRCC is characterized by copy number alterations (CNAs) such as the loss of chromosome 3p and VHL inactivation.