rG4-seq reveals widespread formation of G-quadruplex ... - Nature
Aug 29, 2016 · We introduce RNA G-quadruplex sequencing (rG4-seq), a transcriptome-wide RNA G-quadruplex (rG4) profiling method that couples rG4-mediated reverse transcriptase …
丁一倞研究组发布首个多物种转录组G四联体结构数据库
Oct 25, 2022 · 在所有的RNA结构中，RNA G四联体（RNA G-quadruplex, rG4）是一种重要的RNA三级结构。 它通常富含鸟嘌呤（G-rich）并同时包含Hoogsteen碱基和Watson-Crick碱基 …
RNA G-quadruplexes (rG4s): genomics and biological functions
Jun 4, 2021 · In this review, we will summarize the innovative high-throughput methods recently developed to detect rG4s on a transcriptome-wide scale, highlight the many novel and …
NAR丨郭骏杰/陈硕斌团队开发基于RNA G-四链体的新型PROTAC用于rG4 …
Feb 7, 2025 · RNA G-四链体 (rG4) 是广泛存在于转录组中的非典型二级核酸结构，通过与rG4结合蛋白 (G4BPs) 相互作用，在生命体基因调控过程中起着至关重要的作用，rG4-G4BP复合体已 …
QUADRatlas: the RNA G-quadruplex and RG4-binding proteins …
Jan 6, 2023 · RNA G-quadruplexes (RG4s) are non-canonical, disease-associated post-transcriptional regulators of gene expression whose functions are driven by RNA-binding …
G-Quadruplexes in RNA Biology: Recent Advances and
Apr 1, 2021 · RNA G-quadruplexes (RG4s) are four-stranded structures known to control gene expression mechanisms, from transcription to protein synthesis, and DNA-related processes.
OrensteinLab/rG4detector - GitHub
We present rG4detector, a convolutional neural network for predicting rG4 folding of any given sequence based on rG4-seq data. rG4-seq experimental protocol was employed to generate …
Identification of G-quadruplex nucleic acid structures by high ...
Mar 1, 2025 · G-quadruplexes (G4s) are non-canonical nucleic acid secondary structures formed by guanine-rich DNA or RNA sequences. These structures play pivotal roles in cellular …
Cell | RNA G四链体促进α-synuclein累积 - 网易
Nov 3, 2024 · 近日，来自日本熊本大学的 Yasushi YabukiI 和 Norifumi Shioda 研究团队在 Cell 上发表题为 RNA G-quadruplexes form scaffolds that promote neuropathological a-synuclein …
NAR | 丁一倞研究组发布首个多物种转录组G四联体结构数据库
Oct 25, 2022 · 在所有的RNA结构中，RNA G四联体 （RNA G-quadruplex, rG4） 是一种重要的RNA三级结构。 它通常富含鸟嘌呤 （G-rich） 并同时包含Hoogsteen碱基和Watson-Crick碱 …