Rab7 is a late endosome-/lysosome-associated small GTPase, perhaps the only lysosomal Rab protein identified to date. Rab7 plays critical roles in the endocytic processes. Through …

Overexpression of wild-type rab7 protein allowed normal transport to late endosomes (mannose 6-phosphate receptor positive), while the rab7N125I mutant caused the VSV G protein to …

RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal …

2024年3月27日 · HPO-27 and its human homologue MROH1 are recruited to lysosomes by RAB-7 to mediate the scission of lysosomal tubules. Loss of HPO-27 in C. elegans affects …

2018年1月17日 · Surprisingly, we found that RAB7 not only decorates late endosomes or lysosomes, but is also present on the endoplasmic reticulum, trans -Golgi network, and …

2024年12月25日 · RAB7A (RAB7A, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB7A include Charcot-Marie-Tooth Disease, Axonal, Type 2B and …

Rab5 and rab7 proteins belong to a superfamily of small molecular weight GTPases known to be associated with early and late endosomes, respectively. The rab5 protein plays an important …

Rab7 (or Ypt7 in yeast) is one of the well-characterized members of the Rab family small GTPases, which serve as master regulators of membrane trafficking in eukaryotes. It localizes …

Rab5和rab7蛋白属于小分子GTP酶的超家族，已知分别与早期和晚期内体有关。 rab5蛋白在早期内吞作用中起着重要的调节作用，但是rab7蛋白的功能以前是未知的。 通过比较过度表 …

2011年3月1日 · Rab7, the key regulator in endo-lysosomal trafficking investigated extensively in the past decades, is emerging to govern early-to-late endosomal maturation, microtubule …