RAB27B Gene - GeneCards | RB27B Protein | RB27B Antibody
2024年12月25日 · RAB27B (RAB27B, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB27B include Griscelli Syndrome and Piebald Trait. Among its …
Rab27a and Rab27b control different steps of the exosome
2009年12月6日 · The small GTPases Rab27a and Rab27b and their effectors, Slp4 and Slac2b, control exosome secretion at different steps by regulating the peripheral localization, retention …
Cell Rep丨Rab家族蛋白参与外泌体从上皮细胞顶端或基底外侧质膜 …
2022年6月6日 · 然而，最近的一项研究表明，Rab27A/B-双敲除 (Rab27-DKO) 仅部分阻断了骨髓来源的树突状细胞的外泌体释放，表明Rab27不是Rab家族成员中驱动MVB转运至质膜的唯一 …
Rab27b, a Regulator of Exosome Secretion, Is Associated With
Results: Rab27a and Rab27b knockdown in 58As9 cells decreased the secretion of exosomes, characterized by the endocytic marker CD63. Rab27b knockdown decreased PM in vivo …
RAB27B-regulated exosomes mediate LSC maintenance via
2023年11月30日 · Here, we found that RAB27B, a gene regulating exosome secretion, was overexpressed in LSCs and associated with the poor prognosis of acute myeloid leukaemia …
Rab27a and Rab27b control different steps of the exosome …
Using an RNA interference (RNAi) screen, we identified five Rab GTPases that promote exosome secretion in HeLa cells. Among these, Rab27a and Rab27b were found to function in MVE …
RAB27B调控急性髓系白血病的新机制 - 健康界
2024年1月4日 · 华中科技大学同济医学院附属协和医院刘凌波教授团队等人在leukemia发表了题为“RAB27B-regulated exosomes mediate LSC maintenance via resistance to senescence and …
Rab27b Is Expressed in a Wide Range of Exocytic Cells and …
Rab proteins regulate multiple, complex processes of membrane traffic. Among these proteins, Rab27a has been shown to function specifically in regulated exocytic pathways. However, the …
RAB27B inhibits proliferation and promotes apoptosis of
RAB27B is a member of Ras-like small GTPases that plays a role in endocytosis, exocytosis, and vesicle trafficking. We made an attempt to study the impacts of RAB27B on the proliferation …
RAB27B，成员 RAS 致癌基因家族（RAB27B）基因 | MCE
RAB27B，成员 RAS 致癌基因家族： Rab 蛋白家族的成员，包括 RAB27B，是参与囊泡融合和运输的异戊二烯化膜结合蛋白 (Chen 等人，1997 [PubMed 9066979]) 。[OMIM 提供，2010 年 …