2024年12月25日 · RAB35 (RAB35, Member RAS Oncogene Family) is a Protein Coding gene. Diseases associated with RAB35 include Tetraploidy and Deafness, Onychodystrophy, …

2016年6月21日 · In this review, we provide a comprehensive summary of known Rab35-dependent cellular functions and detail the few Rab35 effectors characterized so far. We also …

Ras-related protein Rab-35 is a protein that in humans is encoded by the RAB35 gene. [5] This GTPase participates in the traffic of recycling endosomes toward the plasma membrane, [6]

2010年1月4日 · Rab35 is a Rab protein with both plasma membrane and endosomal localization, and has been implicated in diverse processes that include T-cell receptor recycling, oocyte …

2022年9月8日 · Here, Rab35 regulates actin polymerization through limiting Rac1 and RhoA activity, which is required to set up proper apicobasal polarity during sprout formation. Our …

2023年4月21日 · Collectively, our findings revealed that RAB35 is required for precise neuronal distribution in the developing hippocampus by regulating the expression of cell adhesion …

2024年12月1日 · Rab35 is a key regulatory GTPase involved in diverse cellular functions, including endocytic recycling, cytokinesis, and the regulation of the actin cytoskeleton. …

2025年2月8日 · Enables GTPase activity and anion binding activity. Involved in several processes, including endosomal transport; plasma membrane to endosome transport; and …

Recently, Rab35 has emerged as a key regulator of cargo recycling at endosomes, with an additional role in regulation of the actin cytoskeleton. Here, we will focus on the regulation of …

2010年4月4日 · We show that Rab35 is the target of TBC1D10A–C and that the inhibition of Rab35 function leads to intracellular accumulation of endosomal vesicles and impairs …