RAB7 is a small GTPase that has the potential of causing malignancy from over 35 tumor types. It is found that RAB7 is an early induced melanoma driver whose levels can define metastatic …

Rab7 is a late endosome-/lysosome-associated small GTPase, perhaps the only lysosomal Rab protein identified to date. Rab7 plays critical roles in the endocytic processes. Through …

2024年12月25日 · RAB7,Ras oncogene superfamily member,likely involved in vesicular transport of proteins from early to late endosomes and lysosomes,expressed in skeletal muscle RAB7A

2017年10月13日 · We have now used a new approach to analyze the role of Rab7: transient expression of Enhanced Green Fluorescent Protein (EGFP)–tagged Rab7 wt and mutant …

2011年3月1日 · Rab7, the key regulator in endo-lysosomal trafficking investigated extensively in the past decades, is emerging to govern early-to-late endosomal maturation, microtubule …

We have now used a new approach to analyze the role of Rab7: transient expression of Enhanced Green Fluorescent Protein (EGFP)–tagged Rab7 wt and mutant proteins in HeLa …

现在，我们已经使用一种新方法来分析Rab7的作用：在HeLa细胞中瞬时表达增强型绿色荧光蛋白（EGFP）标记的Rab7 wt和突变蛋白。 EGFP-Rab7 wt与晚期胞吞结构相关，主要是溶酶 …

Overexpression of wild-type rab7 protein allowed normal transport to late endosomes (mannose 6-phosphate receptor positive), while the rab7N125I mutant caused the VSV G protein to …

Rab蛋白家族是一类Ras相关的GTP结合蛋白,在细胞中发挥确保囊泡转运特异性定位的作用.作为Rab家族的一员,Rab7与其他的Rab成员间既有相似性,又有特异性.其相似性表现在:Rab7与其 …

2009年5月1日 · The small molecular weight G-protein RAB7 is localized to both early and late endosomes and has been shown to be critical for trafficking through the endocytic pathway. …