RAC1/P38 MAPK Signaling Pathway Controls β1 Integrin–Induced ...
2000年1月1日 · Our model depicts a Rac1-dependent pathway generated by the ligation of β1 integrins on human NK cells leading to p38 MAPK activation that controls the production of the …
ERK-MAPK signaling coordinately regulates activity of Rac1 …
2003年7月1日 · The ERK-MAPK pathway controls Fra-1 expression transcriptionally and posttranscriptionally in colon carcinoma cells containing KRAS oncogenes (E.V. and C.J.M., …
Rac1/MAPK/ERK通路在大鼠呼吸机相关性肺损伤中的作用及机制
Ras相关C3肉毒素底物1（Rac1）是G蛋白Ras超家族Rho亚家族的一类小分子GTP蛋白酶，参与细胞迁移、肌动蛋白重组、肿瘤侵袭转移、转录因子调节及血管内皮生成等过程，尤其对细胞骨 …
The Regulatory Roles of Mitogen-Activated Protein Kinase (MAPK ...
Using pharmacological inhibitors of Rac1-Nox2 enzyme complex, we reported the involvement of this holoenzyme and associated oxidative stress in the activation of p38MAPK. These findings …
MAPK Inhibition Requires Active RAC1 Signaling to Effectively Improve ...
2021年11月22日 · In the present study, we found that the recovery of NIS expression induced through MAPK pathway inhibition can be enhanced by potentiating RAC1 activity in thyroid cell …
Two distinct roles of mitogen-activated protein kinases in platelets ...
2009年1月22日 · Mitogen-activated protein kinases (MAPK), p38, and extracellular stimuli-responsive kinase (ERK), are acutely but transiently activated in platelets by platelet agonists, …
ERK-MAPK signaling coordinately regulates activity of Rac1 and ... - PubMed
We describe two signaling events downstream of ERK-MAP kinase contributing to cell motility in colon carcinoma cells. The Fos family member Fra-1 is expressed in an ERK-dependent …
RAC1/P38 MAPK signaling pathway controls beta1 integrin …
The MAP kinase (MAPK) p38 plays a key role in regulating inflammatory responses. Here, we demonstrate that beta1 integrin ligation on human NK cells results in the activation of the p38 …
rac1信号通路在细胞中的功能和参与的过程 - 华美生物
2023年8月8日 · Rac1（Ras-related C3 botulinum toxin substrate 1）是Rho GTPase家族的一员，是细胞内重要的信号传导分子。 Rac1信号通路参与了多种细胞功能和生理过程，包括细胞 …
RAC1/P38 MAPK Signaling Pathway Controls β1 Integrin–Induced ...
2000年1月1日 · Our model depicts a Rac1-dependent pathway generated by the ligation of β1 integrins on human NK cells leading to p38 MAPK activation that controls the production of the …