2024年12月25日 · RAC2 (Rac Family Small GTPase 2) is a Protein Coding gene. Diseases associated with RAC2 include Immunodeficiency 73A With Defective Neutrophil Chemotaxis …

Rac2 (Ras-related C3 botulinum toxin substrate 2) is a small (~21 kDa) signaling G protein (to be specific, a GTPase), and is a member of the Rac subfamily of the family Rho family of …

Rac2 is a 21 kDa small GTPase, a member of the Ras super-family and Rho sub-family of GTPases, that upon activation by a guanine nucleotide exchange factor (GEF), is essential in …

A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency. The Rac2 GTPase contributes to …

2024年2月19日 · Rho GTPases 是一类重要的细胞信号传导蛋白，在细胞内起着关键的调控作用。 它们是小的 GTP酶，属于 Ras超家族，包括RhoA、RhoB、RhoC、Rac1、Rac2、Cdc42等 …

Rac2 mRNA was expressed in the bone marrow of WT recipients of Rac2−/− stem cells and in human mesenchymal stem cells. The data presented here suggest that Rac2 in hematopoietic …

While the genetic absence of Rac2 did not affect osteoclast survival, Rac2 −/− osteoclasts showed reduced basal resorptive activity and a clear defect in the ability to respond to the …

2025年2月9日 · Title: A gain-of-function RAC2 mutation is associated with bone-marrow hypoplasia and an autosomal dominant form of severe combined immunodeficiency. The Rac2 …

2024年4月11日 · Mutations in the small Rho-family guanosine triphosphate hydrolase RAC2, critical for actin cytoskeleton remodeling and intracellular signal transduction, are associated …

该基因编码小鸟苷三磷酸 (GTP) 代谢蛋白 Ras 超家族的成员。 编码的蛋白质定位于质膜，在那里它调节多种过程，例如分泌、吞噬作用和细胞极化。 这种蛋白质的活性也参与活性氧的产生 …