By leveraging state-of-the-art methods in DNA sequencing and circulating tumor cells detection, all powered by artificial intelligence, we have proven that cancer can be found at very early …

Rarecells’ proprietary ISET® (Isolation by Size of Tumor cells) device is a highly accurate, non-invasive liquid biopsy technology, designed to detect cancer earlier and prevent metastases.

We believe that we can develop technology to find a rare cancer cell early enough that it can be eliminated at the start. If cancer is eliminated early, damaging and toxic treatments can be …

2024年12月1日 · In this paper, we propose a single-cell similarity division algorithm (scSID) for identifying rare cells. It takes cell-to-cell similarity into consideration by analyzing both inter …

2015年8月19日 · The development of an algorithm called RaceID enables the identification of rare cell types by single-cell RNA sequencing, even when they are part of a complex mixture of …

2018年11月9日 · Rare cells represent minor cell types in an organism. When the number of profiled cells are in the hundreds, even an outlier cell (singleton) deserves attention. With the …

2020年3月25日 · Blood contains a diverse cell population of low concentration hematopoietic as well as non-hematopoietic cells. The majority of such rare cells may be bone marrow-derived …

We investigate these rare populations in the blood of cancer patients by utilising a wide range of innovative technologies, including CellSearch, Parsortix and High Definition Single Cell Assay …

Rare cell isolation requires special protocols that are gentle and accurate to retain a sufficient amount of healthy target cells. Learn more here.

2025年2月7日 · Some of the most intriguing discoveries have been rare cell populations that, despite their low frequency, have outsized roles in development, homeostasis and disease.

2018年10月4日 · Circulating rare cells (CRCs) are benign or malignant minuscule events in the peripheral blood or other bodily fluids. The detection and quantification of certain CRC types is …

2025年3月13日 · Ultimately, cells become energy-depleted, and this can lead to organ dysfunction and failure. POLG mutations are the most common cause of inherited …

In this article, we describe Rarity, a hybrid semi-supervised framework for cell type identification that has been specifically developed to enable user-controlled sensitivity to rare subpopulations.

2023年12月1日 · In order to balance these competing demands, we have developed a novel statistical framework for unsupervised clustering, named Rarity, that enables the discovery …

2021年7月7日 · Large-scale single cell transcriptomics provide both opportunities and challenges for identifying rare cells playing crucial roles in development and disease. Here, we develop …

In this review, we analyze how this fast technological evolution has improved our understanding of the biological processes with a particular focus on rare cells of the immune system.

The advent of single-cell transcriptomics has made rare cell discovery a mainstream component in the downstream analysis pipeline. Rare cells represent minor cell types in an organism. …

In several clinical studies, counting rare cells can provide valuable information on the status of the patient; examples are the search for circulating tumor cells in peripheral blood, tumor stem …

2023年2月2日 · Researchers at the Hong Kong University of Science and Technology (HKUST) developed a novel technology which allows genomic DNA and RNA sequencing to be carried …

In this review, we analyze how this fast technological evolution has improved our understanding of the biological processes with a particular focus on rare cells of the immune system. We …

2017年4月19日 · This chapter will discuss the detection of some rare cell populations of interest for immunologists and oncologists, along with some crucial technical issues, along with the …

2025年3月20日 · Encelto is small, semi-permeable capsule implanted in the eye that contains allogeneic retinal pigment epithelium cells genetically engineered to produce specific …

2025年3月21日 · Quantification of TRECs in low-frequency memory T subpopulations e.g. T stem cell memory cells (which constitute 2–4% of the total CD4 + and CD8 + T cell population in …

2025年3月18日 · A new part of an ocean plant cell has been discovered that might revolutionize farming one day. ... The DNA also appeared to have a special and rare function — of taking …

2025年3月21日 · A groundbreaking basket clinical trial focused on a pair of rare mitochondrial diseases has reached a pivotal milestone, with its official registration on ClinicalTrials.gov. The …

March 7, 2025 – The FDA has approved a new gene therapy for macular telangiectasia type 2 (MacTel), a rare eye disease that causes vision loss. The approval marks the first and only …

2 天之前 · MIWI2, a PIWI Argonaute protein known for suppressing retrotransposons during male gonadogenesis, has an unexplored role in mammalian somatic cells. We identify MIWI2 …