G3BP1 restricts HIV-1 replication in macrophages and T-cells by ...
2015年12月1日 · We were able to confirm that there was no unspecific precipitation of cellular RNA or G3BP1 by including normal IgG antibodies as RIP negative control. Additionally, the …
G3BP1 inhibits RNA virus replication by positively regulating RIG …
2019年12月11日 · Retinoic acid-inducible gene I (RIG-I) is a pattern recognition receptor and is involved in the innate immune response against RNA viruses infection. Here, we demonstrate …
The association of UBAP2L and G3BP1 mediated by small ... - Nature
2023年4月14日 · Our RIP assay and in vitro binding assay revealed that UBAP2L association with G3BP1 was mediated by snoRNAs. There are two types of snoRNAs, C/D box snoRNAs and …
Profiling dynamic RNA–protein interactions using small ... - Nature
2023年6月22日 · In this study, we developed targets of RBPs identified by editing induced through dimerization (TRIBE-ID), a facile strategy for quantifying state-specific RNA–protein …
The stress granule protein G3BP1 binds viral dsRNA and RIG-I …
The stress granule protein G3BP1, known to arrest mRNA translation, was identified as a regulator of RIG-I–induced IFN-β production. How G3BP1 functions in RIG-I signaling is not …
G3BP-driven RNP granules promote inhibitory RNA-RNA …
2025年2月6日 · Ribonucleoprotein (RNP) granules have been linked to translation regulation and disease, but their assembly and regulatory mechanisms are not well understood. Here, we …
G3BP1-linked mRNA partitioning supports selective protein …
2020年5月14日 · To study transcript partitioning under cell stress, we catalogued mRNAs enriched in prostate carcinoma PC-3 cell PSs, as defined by polysome fractionation and RNA …
The roles of G3BP1 in human diseases (review) - ScienceDirect
2022年5月5日 · Ras-GTPase-activating protein binding protein 1 (G3BP1) is a multifunctional binding protein involved in a variety of biological functions, including cell proliferation, …
G3BP1 and SLU7 Jointly Promote Immune Evasion by …
2023年12月12日 · To investigate the mechanism by which G3BP1 activates PI3K/Akt signaling, we performed RNA immunoprecipitation sequencing (RIP-seq) using UMUC3 cells that stably …
应激颗粒核心元素 G3BP1 在各种疾病中的应用：综 …
2024年11月6日 · Ras-GTP 酶激活蛋白结合蛋白 1 （G3BP1） 是应激颗粒 （SGs） 的核心组分和关键调节开关。 当细胞内游离 RNA 的浓度增加时，它可以触发以 G3BP1 为核心的 RNA 依 …