The renal outer medullary potassium channel (ROMK) is an ATP-dependent potassium channel (K ir 1.1) that transports potassium out of cells. It plays an important role in potassium …

肾外髓钾通道(renal outer medullary potassium channel, ROMK)是内向整流钾通道超家族成员,介导肾小管上皮细胞内K+ 向小管腔的转运,在维持机体钾稳态方面发挥重要作用。

The apically located renal outer medullary K + (ROMK) channel provides a pathway for K + to recycle from cell to lumen, and ensures an adequate supply of K + to sustain Na +-K +-2Cl − …

Here we provide a comprehensive guide to ROMK, spanning from the physiology in the kidney to the organization and regulation by intracellular factors to the structural basis of its function at …

钾离子（紫色）通过钾离子通道的俯视图（PDB 1BL8）。 在 细胞生物学 的范畴， 钾离子通道 是最广泛分布的 离子通道，且几乎存在大多数的生物中。 [1] 它们具有钾离子选择性的孔洞在 …

2018年1月14日 · 这个 ROMK，即 the renal outer-medullary K+ channel，是今天要说的一个重要结构，有个很拗口的中文名称：肾脏外髓钾通道。 也有称之为 KIR1.1，学名应该 …

This brief review attempts to provide an overview regarding recent developments in the regulation of ROMK channels. Studies performed in ROMK null mice suggest that ROMK cannot only …

The ability of intracellular and extracellular Mg2+ to block secretory K+ currents through ROMK channels under physiologic conditions is incompletely understood. We expressed ROMK2 …

ROMK is a gene encoding inwardly rectifying adenosine triphosphate regulated K+ channels. Alternative splicing of ROMK exons yields several different transcripts, ROMK 1-3, that are …

In recent years, understanding of the physiological role of the renal outer medullary potassium (ROMK) channels, has shown an intriguing pharmacological target for developing an …