
【国自然热点】第一弹:线粒体氧化应激!一文吃透该热点的10大 …
2022年10月22日 · 大量研究表明,以线粒体通透性转换孔(mptp)开放和活性氧(ros)水平升高、线粒体膜电位(mmp)降低为表现的线粒体功能障碍在神经性疼痛的发生发展中起重要作用。
ATP and ROS signal cell extrusion - Nature
2022年4月14日 · Mori et al. now identify ATP and reactive oxygen species (ROS) as key upstream cues for cell extrusion. Extrusion of transformed cells involves their competition with …
ROS production by mitochondria: function or dysfunction?
2023年12月11日 · In eukaryotic cells, ATP generation is generally viewed as the primary function of mitochondria under normoxic conditions. Reactive oxygen species (ROS), in contrast, are …
In vivo real-time dynamics of ATP and ROS production in axonal ...
2019年6月11日 · Mitochondria are critical for the function and maintenance of myelinated axons notably through Adenosine triphosphate (ATP) production. A direct by-product of this ATP …
国自然热点追踪——线粒体功能障碍与氧化应激分子机制与研究思 …
线粒体呼吸链 是能量产生的核心,因为它将呼吸链复合物之间的电子转移与穿过线粒体内膜的质子传递相结合,以产生 ATP 合成所需的电化学梯度。 除了对能量产生至关重要外,呼吸链还是 …
Calcium, ATP, and ROS: a mitochondrial love-hate triangle
The mitochondrion is at the core of cellular energy metabolism, being the site of most ATP generation. Calcium is a key regulator of mitochondrial function and acts at several levels …
Mitochondrial electron transport chain: Oxidative phosphorylation ...
2020年10月1日 · The mitochondrial electron transport chain utilizes a series of electron transfer reactions to generate cellular ATP through oxidative phosphorylation. A consequence of …
The Complex Interplay between Mitochondria, ROS and Entire …
In addition to the production of energy in the form of ATP, mitochondria play a crucial role in the entire cell physiology through their participation in many metabolic and signaling pathways. …
线粒体产生 ROS:功能还是功能障碍?,Oncogene - X-MOL
在真核细胞中,ATP 生成通常被视为常氧条件下线粒体的主要功能。 相比之下,活性氧(ROS)被认为是呼吸的副产品,与功能障碍和疾病广泛相关。 近年来,线粒体 ROS 的重要 …
Elevated ROS depress mitochondrial oxygen utilization efficiency …
Mitochondria are important sites for the production of ATP and the generation of ROS in cells. However, whether acute hypoxia increases ROS generation in cells or affects ATP production …