ROS-dependent activation of JNK converts p53 into an efficient ... - PubMed
ROS promote the activation of c-Jun N-terminal kinase (JNK) and DNA damage response, which establishes a positive feedback loop with p53. This converts the p53-induced growth …
JNK signaling pathway is a key modulator in cell death ... - PubMed
2006年3月15日 · In this review we will first summarize and discuss some recent findings regarding the signaling mechanisms of ROS-or RNS-mediated JNK activation. Second, we will …
ROS介导JNK信号通路的研究进展 - 豆丁网
2011年10月27日 · 摘要：c-JunN端激酶 (JNK)通路是细胞感受外界环境变化的重要途径，与细胞增殖、分化、凋亡等生命过程息息相关。 活性氧 (ROS) 具有很高的生物学活性，可作为第二信 …
Reactive oxygen species and cell signaling. Review
2024年2月1日 · Reactive oxygen species (ROS) activate JNK, p38 and ERK mitogen-activated protein kinases (MAPK), which upregulate c-Jun and c-Fos expression at the transcriptional …
Reactive oxygen species mediate crosstalk between NF-κB and JNK
2005年12月9日 · Further studies have also revealed that NF- κ B inhibits JNK activation by suppressing accumulation of reactive oxygen species (ROS). In this review, we will focus on …
活性氧/c-Jun氨基末端激酶/核因子-κB信号分子通过调控凋亡参与 …
ROS are involved in regulating the activation of c-Jun N-terminal kinase (JNK)/nuclear factor kappa-B (NF-κB) signaling molecules. When the signaling molecules are overactivated by …
JNK signaling pathway is a key modulator in cell death mediated …
2006年3月15日 · In this review, we aim to summarize recent findings on the regulatory role of ROS and RNS in JNK activation, especially on the following aspects: (i) the molecular …
ROS-Induced JNK and p38 Signaling Is Required for Unpaired
2015年10月23日 · Propagated ROS activate p38 and induce tolerable levels of JNK. The activation of JNK and p38 results in the expression of the cytokines Unpaired (Upd), which …
ROS介导JNK信号通路的研究进展 - 百度学术
c-junn端激酶(jnk)通路是细胞感受外界环境变化的重要途径,与细胞增殖、分化、凋亡等生命过程息息相关.活性氧(ros)具有很高的生物学活性,可作为第二信使参与到jnk信号通之中.ros可通 …
Myricetin and dihydromyricetin as JNK1 inhibitors protect against ROS …
2024年5月6日 · It was found that reactive oxygen species (ROS)-mediated JNK signaling pathway is closely associated with oxidative stress. Sánchez-Chávez et al. have shown that …