Reactive oxygen species: production and role in the kidney
Reactive oxygen species (ROS) are formed by incomplete reduction of molecular oxygen. They include superoxide anion (O2-.), hydrogen peroxide (H2O2), hydroxyl radical (OH.), and …
Reactive Oxygen Species and Redox Signaling in Chronic Kidney …
Accumulating evidence indicates that elevated intracellular levels of reactive oxygen species (ROS) play a major role in the pathogenesis of CKD. Increased intracellular levels of ROS can …
Oxidative stress and the role of redox signalling in chronic kidney ...
2023年10月19日 · This Review describes the relevance of ROS to physiological processes and disease pathogenesis with a focus on the kidney. The authors also outline the current status of …
Reactive Oxygen Species and Redox Signaling in Chronic Kidney Disease
2020年5月28日 · Accumulating evidence indicates that elevated intracellular levels of reactive oxygen species (ROS) play a major role in the pathogenesis of CKD. Increased intracellular …
Oxidant Mechanisms in Renal Injury and Disease - PMC
The role of ROS and RNS is considered a critical factor involved in initiation and progression of various mammalian kidney diseases and injuries, including diabetic nephropathy, hypertension …
Mitochondria ROS and mitophagy in acute kidney injury
2022年6月9日 · The relationship between mitochondria oxidative stress, ROS production and mitophagy are intimately interwoven, and these processes are all involved in various …
NADPH Oxidases, Reactive Oxygen Species, and the Kidney: …
ROS generated by NADPH oxidases regulate renal glucose production and glucose handling. The kidney contributes to glucose homeostasis by producing glucose from glutamine …
Reactive Oxygen Species and Redox Signaling in Chronic Kidney
2020年3月31日 · Accumulating evidence indicates that elevated intracellular levels of reactive oxygen species (ROS) play a major role in the pathogenesis of CKD. Increased intracellular …
Antioxidant nanozymes in kidney injury: mechanism and application
2023年7月21日 · Effective scavenging of ROS can delay or halt the progression of kidney injury by reducing inflammation and oxidative stress. With the development of nanotechnology and …
Reactive Oxygen Species in Cystic Kidney Disease - MDPI
2024年9月30日 · Oxidative stress and reactive oxygen species (ROS) can significantly alter its pathophysiology, clinical outcomes, and treatment, contributing to negative outcomes, …