2024年12月25日 · RSPO2 (R-Spondin 2) is a Protein Coding gene. Diseases associated with RSPO2 include Humerofemoral Hypoplasia With Radiotibial Ray Deficiency and Tetraamelia …

R-spondin 2 also known as roof plate-specific spondin-2 is a secreted protein that in humans that is encoded by the RSPO2 gene. [5] R-spondin 2 synergizes with canonical WNT to activate …

2018年8月14日 · Previous work has shown that R-spondin-2 (Rspo2, RSPO2) is both highly expressed in Wnt-stimulated pre-osteoblasts and its overexpression induces osteoblast …

RSPO2 is dynamically expressed during midbrain development and promotes the dopaminergic differentiation of mouse and human neuroblasts. Furthermore, they show that RSPO2 induced …

The RSPO2 gene provides instructions for making a protein called R-spondin-2. R-spondin-2 plays a role in the Wnt signaling pathway, a series of steps that affect the way cells and …

2020年4月27日 · R-spondin2 (RSPO2) is a member of the R-spondin family, which are secreted activators of the WNT/β-catenin (CTNNB1) signaling pathway. In the mouse postnatal ovary, …

2025年2月8日 · RSPO2 is a novel target gene of the NOBOX key transcription factor, confirming its important role during the follicular growth in ovary. However, RSPO2 mutations are rare or …

2023年6月25日 · Based on the latest research progress, this paper reviews the structure and main functions of Rspo2, the mechanism of Rspo2 regulating Wnt/β-catenin signaling pathway …

2021年10月18日 · R-spondin (RSPO) proteins constitute a family of four secreted glycoproteins (RSPO1–4) that have appeared as multipotent signaling ligands. The best-known molecular …

R-spondin2, a co-activator of WNT/β-catenin signaling, plays an important role in embryonic murine lung development. However, the role of Rspo2 in adult lung homeostasis and …