S100 calcium-binding protein A10 (S100A10), also known as p11, is a protein [5] that is encoded by the S100A10 gene in humans and the S100a10 gene in other species. [6] [7] S100A10 is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range ...

2024年12月25日 · S100A10 (S100 Calcium Binding Protein A10) is a Protein Coding gene. Diseases associated with S100A10 include Trachea Leiomyoma and Synovium Neoplasm. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Regulation of CFTR activity (norm and CF).

2019年8月29日 · Mechanistically, S100A10 regulated macrophage inflammatory responses by interfering with the appropriate recruitment and activation of the receptor-proximal signaling components and...

S100A10 (p11, annexin II light chain, calpactin light chain) is a multifunctional protein with a wide range of physiological activity. S100A10 is unique among the S100 family members of proteins since it does not bind to Ca 2+, despite its sequence and structural similarity. This review focuses on studies highlighting the structure, regulation ...

2021年7月2日 · S100A10, a member of the S100 family of Ca 2+-binding proteins, is a widely distributed protein involved in many cellular and extracellular processes. The best recognized role of S100A10 is the regulation, via interaction with annexin A2, …

由该基因编码的蛋白质是包含 2 个 EF 手钙结合基序的 S100 蛋白质家族的成员。 S100 蛋白定位于多种细胞的细胞质和/或细胞核，并参与许多细胞过程的调节，例如细胞周期进程和分化。 S100 基因包括至少 13 个成员，它们成簇地位于染色体 1q21 上。 这种蛋白质可能在胞吐作用和胞吞作用中起作用。 [RefSeq 提供，2008 年 7 月] The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs.

S100A10 promotes cancer metastasis via recruitment of MDSCs within the lungs. Accumulation of annexin A2 and S100A10 prevents apoptosis of apically delaminated, transformed epithelial cells. [S100A10 promotes proliferation and invasion of lung adenocarcinoma cells by activating the Akt-mTOR signaling pathway].

2018年9月11日 · S100A10 (p11), a member of the S100 family of small dimeric EF-hand-type Ca 2+ -binding proteins, plays a role in a variety of both intracellular and extracellular processes. Previous studies...

S100A10（p11、膜联蛋白 II 轻链、钙肽素轻链）是一种具有广泛生理活性的多功能蛋白。 S100A10 在 S100 蛋白质家族成员中是独特的，因为它不与 Ca2+ 结合，尽管其序列和结构相似。 本综述重点关注 S100A10 的结构、调控和结合伙伴的研究。 对S100A10的结合配偶体进行了整理和总结。 S100A10 (p11, annexin II light chain, calpactin light chain) is a multifunctional protein with a wide range of physiological activity.

2018年12月19日 · The aims of this review are to highlight the current understanding of S100A10 function in cancer cells—with a particular focus on ovarian cancer—and to discuss the potential for using S100A10 as a predictive marker and targeting S100A10 to inhibit cancer progression and treatment resistance.