2024年4月11日 · The suprachiasmatic nucleus (SCN) is the mammalian central circadian pacemaker with heterogeneous neurons acting in concert while each neuron harbors a self …

The suprachiasmatic nucleus or nuclei (SCN) is a small region of the brain in the hypothalamus, situated directly above the optic chiasm.

2020年2月17日 · We have used single-cell RNA-sequencing to identify the basic cell types in the mouse SCN and to characterize their circadian and light-induced gene expression patterns. …

In this review, we will discuss the function of the SCN as a master circadian pacemaker tissue, focusing on cell autonomy and network properties. The circadian clock that operates in …

2018年8月6日 · In this primer, we shall briefly review the historical identification of the SCN as the master circadian clock, and then discuss it on three different levels: the cell-autonomous SCN, …

2024年12月6日 · Circadian rhythms in mammals arise from the spatiotemporal synchronization of ~20,000 neuronal clocks in the Suprachiasmatic Nucleus (SCN). While anatomical, molecular, …

2023年7月19日 · The suprachiasmatic nucleus (SCN), consisting of ∼20,000 cells, has been known as the master circadian pacemaker in mammals. 7 Light information enters the SCN …

2003年9月30日 · In mammals, the suprachiasmatic nucleus (SCN) contains a biological clock that drives circadian rhythms in vivo and in vitro. Primary dissociated neuronal culture is a useful …

The suprachiasmatic nucleus (SCN) is the master circadian pacemaker in mammals. SCN is a heterogeneous nucleus composed of a variety of cell types. These different cell types may …

We have used single-cell RNA-sequencing to identify the basic cell types in the mouse SCN and to characterize their circadian and light-induced gene expression patterns. We identified eight …