SGK1 - Wikipedia
Serine/threonine-protein kinase Sgk1 also known as serum and glucocorticoid-regulated kinase 1 is an enzyme that in humans is encoded by the SGK1 gene. SGK1 belongs to a subfamily of …
SGK1 Gene - GeneCards | SGK1 Protein | SGK1 Antibody
2024年12月25日 · SGK1 (Serum/Glucocorticoid Regulated Kinase 1) is a Protein Coding gene. Diseases associated with SGK1 include Gastric Cancer and Pseudohypoaldosteronism. …
Serum and glucocorticoid-regulated kinase 1 (SGK1) as an …
2024年10月1日 · Multiple research findings have indicated that SGK1 is associated with heart disease due to its involvement in cardiac hypertrophy and fibrosis. This article reviews different …
血清/糖皮质激素调节激酶 1（Sgk1）基因 | MCE
该基因编码在细胞应激反应中起重要作用的丝氨酸/苏氨酸蛋白激酶。 这种激酶激活某些钾、钠和氯通道，表明参与细胞存活、神经元兴奋性和肾钠排泄等过程的调节。 这种酶被蛋白质磷酸 …
SGK1功能的研究进展及临床意义 - 百度学术
血清和糖皮质激素诱导蛋白激酶 (SGKs)是一种AGC家族的丝氨酸苏氨酸蛋白激酶,其包括位于不同染色体的三个基因编码的蛋白激酶 (SGK1,SGK2,SGK3). SGKs主要由磷脂酰肌醇-3-激酶 ( …
Serum and glucocorticoid-regulated kinase 1: Structure, biological ...
Serum and glucocorticoid-regulated kinase 1 (SGK1) is a member of the protein kinase A, G, and C (AGC) family (Firestone et al., 2003). SGK1 was first identified in rat mammary gland tumor …
SGK1 in Human Cancer: Emerging Roles and Mechanisms
2021年1月19日 · This review systematically summarizes and discusses the role of SGK1 as a diagnostic and prognostic biomarker of diverse cancer types; focuses on its essential roles …
SGK1 negatively regulates inflammatory immune responses and …
2022年6月1日 · Serum- and glucocorticoid-regulated kinase 1 (SGK1) is a serine/threonine kinase that plays important roles in the cellular stress response. While SGK1 has been reported to …
The prospect of serum and glucocorticoid-inducible kinase 1 (SGK1…
2020年7月15日 · The functions of SGK1 include regulating tumor growth, survival, metastasis, autophagy, immunoregulation, calcium (Ca 2+) signaling, cancer stem cells, cell cycle, and …
阿尔茨海默症新靶点——Sgk1 - 知乎 - 知乎专栏
研究人员给予了小鼠Sgk1特异性抑制剂GSK650394，并观察到高磷酸化tau蛋白水平显著降低，前额叶皮层谷氨酸能突触的功能发生恢复，AD小鼠的记忆障碍也得到了改善。