2021年8月16日 · sln和nlc表现出更好的物理稳定性，解决了基于脂质体制剂的一个主要问题。 SLN和NLC还具有更高的负载能力和更高的生物利用度，易于大规模生产，无需使用有机溶剂，并且比其他 LNP相比经历灭菌时更稳定。

2009年1月21日 · Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC) by the composition of the solid particle matrix. Both are an alternative carrier system to liposomes and emulsions. This review paper focuses on …

2002年11月1日 · As a novel type of lipid nanoparticles with solid matrix, the nanostructured lipid carriers (NLC) are presented, the structural specialities described and improvements discussed, for example, increase in loading capacity, physical and chemical long-term stability, triggered release and potentially supersaturated topical formulations.

2023年5月25日 · SLNs are solid colloidal particles in the sub-micron range, ranging from 4 to 1000 nm, and contain in their formulation physiological, biodegradable, and biocompatible lipids and surfactants, which can incorporate both lipophilic and hydrophilic drugs inside the lipid matrix.

Solid lipid nanoparticles (SLNs) and nanostructured lipid carriers (NLCs) are two major types of Lipid-based nanoparticles.

We discuss the selection criteria for lipids, surfactants, and surface modifiers commonly in use in SLN/NLC, their production techniques, and the range of drugs loaded in these lipid nanoparticles for the treatment of skin disorders.

Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), which are prepared with physiologically inert lipids, therefore emerged as an ideal strategy to bypass toxicities issues and avoid the use of organic solvents in their formulations.

通过在室温下将少量脂质液体引入sln来设计nlc，可降低脂质核的结晶度。 NLC结晶度的降低抑制了药物从基质中的排出，增强了纳米颗粒的载药能力和理化长期稳定性。

2009年1月21日 · Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC) by the composition of the solid particle matrix. Both are an alternative carrier system to liposomes and emulsions. This review paper focuses on …

2009年1月21日 · Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC) by the composition of the solid particle matrix. Both are an alternative carrier system to liposomes and emulsions. This review paper focuses on …