Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-β …
1998年8月27日 · Flag-tagged Smad3 and Myc-tagged Sm ad4 were detected by immunoblottng using anti-Flag M2 antibody (Kodak, IBI) or anti-Myc 9E10 antibody. c-Jun was detected using …
经典信号通路总结——TGF-β信号通路 - 知乎 - 知乎专栏
通常 TGF-β信号通路 的下游的效应转录因子是 SMAD。 该通路的信号来源有两类：TGF-β1/2/3和 BMP （骨形态发生蛋白）。 要检测TGF-β通路活性一般检测TGF-β、TGF-β的受体、SMAD或 …
TGFβ and EGF signaling orchestrates the AP-1- and p63 ... - Nature
2020年4月29日 · Various JUN and FOS members have been found to interact with SMADs [25, 30, 31], and JUNB triggers activation of a TGFβ-induced SMAD-dependent breast cancer …
Smad3 and Smad4 cooperate with c-Jun/c-Fos to mediate TGF-beta ... - PubMed
1998年8月27日 · Smad3 and Smad4 also act together with c-Jun and c-Fos to activate transcription in response to TGF-beta, through a TGF-beta-inducible association of c-Jun with …
Smad3/AP-1 interactions control transcriptional responses to
2001年6月22日 · In this report, we have investigated the functional interactions of the Smad and AP-1 transcription factors. We demonstrate that Smad and AP-1 complexes specifically bind …
Smad7 Enhances TGF-β-Induced Transcription of c-Jun and …
2020年9月25日 · Smad7 expression is induced by TGF-β to control TGF-β signaling in a negative feedback manner. Here we report an additional function of Smad7, i.e., to enhance TGF-β …
Smads bind directly to the Jun family of AP-1 transcription factors
1999年4月4日 · The Smad interacting region of JunB maps to a C-terminal 20-amino acid sequence that is partially conserved in cJun and JunD. We show that Smad3 and Smad4 also …
Smads直接与AP-1转录因子的Jun家族结合。,Proceedings of the …
体外结合研究表明，Smad3和Smad4均结合了所有三个Jun家族成员：JunB，cJun和JunD。 JunB的Smad相互作用区域映射到cJun和JunD中部分保守的C端20个氨基酸序列。 我们显 …
Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad ... - PubMed
2001年4月26日 · Smad proteins transduce signals from TGF-beta receptors and regulate transcription of target genes. Among the latter are c-jun and junB, which encode members of …
Smad3 和 Smad4 与 c-Jun/c-Fos 协同介导 TGF-β 诱导的转 …
1998年8月27日 · 这种 TGF-β 转录激活机制，通过 Smad3-Smad4 和 c-Jun-c-Fos 之间的功能和物理相互作用，表明 Smad 信号和 MAPK/JNK 信号会聚在 AP1 结合启动子位点。 "点击查看英 …
- 某些结果已被删除