
SMARCB1 Gene - GeneCards | SNF5 Protein | SNF5 Antibody
2024年12月25日 · SMARCB1 (SWI/SNF Related BAF Chromatin Remodeling Complex Subunit B1) is a Protein Coding gene. Diseases associated with SMARCB1 include Coffin-Siris …
SMARCB1 - Wikipedia
SWI/SNF -related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 is a protein that in humans is encoded by the SMARCB1 gene. [5][6][7] The protein encoded …
SMARCB1-Deficient Cancers: Novel Molecular Insights and …
Loss of SMARCB1 has been implicated in the initiation of cancers such as malignant rhabdoid tumor (MRT), atypical teratoid rhabdoid tumor (ATRT), and, more recently, renal medullary …
Targeting DCAF5 suppresses SMARCB1 -mutant cancer by
2024年3月27日 · We report that the little-studied gene DDB1–CUL4-associated factor 5 (DCAF5) is required for the survival of SMARCB1 -mutant cancers. We show that DCAF5 has a quality …
SMARCB1基因缺失与胰腺癌 - 知乎 - 知乎专栏
2023年11月10日 · smarcb1 del表明smarcb1基因缺失,导致swi/snf亚基水平降低,亚基融入染色质复合物减少(pmid: 27941797),以及细胞培养中egfr和met通路信号的过度激活(pmid: …
SMARCB1-Deficient Cancers: Novel Molecular Insights and
2022年7月27日 · SMARCB1 is a critical component of the BAF complex that is responsible for global chromatin remodeling. Loss of SMARCB1 has been implicated in the initiation of …
SMARCB1 SWI/SNF related BAF chromatin remodeling complex …
SMARCB1 Promotes Ubiquitination and Degradation of NR4A3 via Direct Interaction Driven by ROS in Vascular Endothelial Cell Injury. SMARCB1 loss interacts with neuronal differentiation …
SMARCB1 gene - MedlinePlus
The SMARCB1 gene provides instructions for making a protein that forms one piece (subunit) of several different protein groupings called SWI/SNF protein complexes. Learn about this gene …
SMARCB1-mediated SWI/SNF complex function is essential for enhancer ...
SMARCB1 (also known as SNF5, INI1, and BAF47), a core subunit of the SWI/SNF (BAF) chromatin-remodeling complex, is inactivated in nearly all pediatric rhabdoid tumors. These …
Gene of the month: SMARCB1 - PMC
In this review, we give a general overview of SMARCB1, its role in various cancers including germline mutations, association with genetic syndromes and role in future targeted therapies. …