SMC4 Gene - GeneCards | SMC4 Protein | SMC4 Antibody
Dec 25, 2024 · SMC4 (Structural Maintenance Of Chromosomes 4) is a Protein Coding gene. Diseases associated with SMC4 include Pleural Empyema and Meningioma, Familial. Among …
SMC4 - Wikipedia
Structural maintenance of chromosomes protein 4 (SMC-4) also known as chromosome-associated polypeptide C (CAP-C) or XCAP-C homolog is a protein that in humans is encoded …
SMC4, which is essentially involved in lung development, is
Sep 30, 2016 · Structural maintenance of chromosome 4 (SMC4) is a core subunit of condensin complexes that mainly contributes to chromosome condensation and segregation....
SMC4, a novel tumor prognostic marker and potential tumor …
The structural maintenance of chromosome 4 (SMC4) is a member of the ATPase family of chromosomes. The most widely reported function of SMC4, as well as the remaining subunits …
Overexpression of SMC4 activates TGFβ/Smad signaling and
Mar 13, 2017 · Structural maintenance of chromosomes 4 (SMC4), an SMC family member, encodes the SMC4 protein that is highly expressed in multiple tumors, suggesting an oncogenic...
The many functions of smc proteins in chromosome dynamics
Oct 1, 2002 · The six highly conserved structural maintenance of chromosomes (SMC) proteins form three types of heterodimer (SMC1–SMC3, SMC2–SMC4, SMC5–SMC6), which are core …
SMC4在信号通路及其在肿瘤疾病中作用的研究进展_蔡伟文 - 道客 …
Aug 1, 2023 · 而SMC4作为SMC家族的一员，既具有上述功能，又参与调控了TGF－β／Smad、JAK2／Stat3、PI3K／Akt和NF－κB等通路，同时它还在血液、呼吸、消化、生殖等系统肿瘤 …
Cell子刊：刘连新/吴缅团队揭示癌细胞非遗传性化疗耐药新机制
Aug 9, 2023 · smc4是一种保守的atp酶，参与有丝分裂过程中染色体的聚集和分离。 然而，SMC4不仅介导染色体聚集，还影响DNA损伤修复、DNA重组和基因组的普遍转录。 此 …
SMC4对人乳腺癌细胞增殖、迁移及侵袭能力的影响及其机制研究
Sep 14, 2024 · 染色体结构维持蛋白4(structural maintenance of chromosome 4，SMC4)是SMC的核心成员之一，在有丝分裂过程染色体的凝集和分离中发挥着重要作用[2-3]。此外，有研究指 …
SMC4，一种新型肿瘤预后标志物和潜在的肿瘤治疗靶点,Frontiers …
Mar 17, 2023 · 4 号染色体 (SMC4) 的结构维护是染色体 ATPase 家族的成员。 SMC4 以及整个凝聚蛋白复合物的其余亚基最广泛报道的功能是姐妹染色单体的压缩和解离、DNA 损伤修复 …
SMC4 structural maintenance of chromosomes 4 [ (human)]
Feb 9, 2025 · Study found that mRNA expression of SMC4 was upregulated in invasive breast cancer cells. Patients with high mRNA level of SMC4 suffered different survival with triple …
The diapause-like colorectal cancer cells induced by SMC4 …
Here, we establish a multifarious role for SMC4 in the switching of colorectal cancer cells to a diapause-like state. SMC4 attenuation promotes the expression of three investment phase …
SMC4, a novel tumor prognostic marker and potential tumor
Mar 17, 2023 · The structural maintenance of chromosome 4 (SMC4) is a member of the ATPase family of chromosomes. The most widely reported function of SMC4, as well as the remaining …
Cell cycle regulation of condensin Smc4 - PMC
These studies have revealed the novel finding that condensin protein levels are cell cycle regulated and have identified the factors necessary for Smc4 proteolysis. Keywords: …
黏连蛋白 - 百度百科
【SMC（structuralmaintenance of chromosome）蛋白家族包括Smc1、Smc2、Smc3、Smc4等，其中Smc2和Smc4是细胞分裂中另一种重要蛋白—— 凝缩蛋白 （condensin）的组成部分 …
Fight, flight, and freeze!: Cell Metabolism - Cell Press
Sep 5, 2023 · In light of this, in the latest issue of Cell Metabolism, Sun et al. have revealed structural maintenance of chromosomes 4 (SMC4) as a novel molecular regulator of cellular …
Frontiers | SMC4, a novel tumor prognostic marker and potential …
Mar 16, 2023 · Structural maintenance of chromosome 4 (SMC4), a member of the chromosome ATPase family, is a class of proteins evolutionarily conserved from bacteria to humans (1).
4 号染色体的结构维护（SMC4）基因 | MCE - MCE-生物活性 ...
该基因属于“染色体结构维护” (SMC) 基因家族。 该基因家族的成员在染色体有丝分裂分离过程中染色体结构的两个变化中发挥作用——染色体浓缩和姐妹染色单体内聚。 由该基因编码的蛋白 …
SMC4 Gene - Somatic Mutations in Cancer - Wellcome Sanger …
SMC4 - Explore an overview of SMC4, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data.
Condensin Smc4 promotes inflammatory innate immune response …
Through a high-throughput screening of the epigenetic modifiers, we identified Smc4, a core subunit of condensin, to potentially promote inflammatory innate immune response. …