2024年12月25日 · SOD1 (Superoxide Dismutase 1) is a Protein Coding gene. Diseases associated with SOD1 include Spastic Tetraplegia And Axial Hypotonia, Progressive and …

SOD1 is a 32 kDa homodimer which forms a beta barrel (β-barrel) and contains an intramolecular disulfide bond and a binuclear Cu/Zn site in each subunit.

6 天之前 · Gene target information for SOD1 - superoxide dismutase 1 (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.

Soluble cytoplasmic SOD1 is a copper- and zinc-containing enzyme; the SOD1 gene maps to chromosome 21q22 (Sherman et al., 1983). SOD2 (147460) is a distinct mitochondrial enzyme …

图1. SOD1基因及其结合蛋白。 上方是能够调控SOD1表达相关分子的汇总。 DOI: 10.3390/ijms19051345 除了神经元自身的SOD1对其功能产生影响外， 星形细胞 也会释放突变 …

SOD1 is a homodimeric protein in which each monomer is comprised of a 153-residue chain that adopts a β-sandwich fold. Each monomer is stabilized by an intramolecular disulfide bridge and...

Map: This gene SOD1 maps on chromosome 21, at 21q22.1|21q22.11 according to Entrez Gene. In AceView, it covers 12.31 kb, from 33029837 to 33042146 (NCBI 37, August 2010), on the …

SOD1 maps to chromosomal location 21q22.11 and encodes for a 17 kDa protein ( Figure 1B). The encoded product, SOD1, is an enzyme which catalyses the removal of superoxide …

2019年12月4日 · 超氧化物歧化酶（SOD）是细胞抗氧化防御级联的主要酶。 人胞质 SOD 的错误折叠、伴随的寡聚化和高阶聚集与肌萎缩侧索硬化症 (ALS) 相关。 尽管具有两个金属离子辅 …

In the early steps of SOD1 maturation and its intracellular transport to mitochondrial inter-membrane space, the protein in its monomeric metal-free state is highly disordered in solution, …