Sterol regulatory element-binding protein 1 - Wikipedia
Sterol regulatory element-binding transcription factor 1 (SREBF1) also known as sterol regulatory element-binding protein 1 (SREBP-1) is a protein that in humans is encoded by the SREBF1 …
SREBP - 百度百科
Sterol-regulatory element binding proteins (SREBPs)胆固醇调节元件结合蛋白(SREBP)是位于内质网的细胞内胆固醇敏感器，通过Insig-Srebp-Scap途径对细胞内胆固醇进行反馈调节。
Sterol regulatory element-binding protein - Wikipedia
SREBP-1c is responsible for regulating the genes required for de novo lipogenesis. [6] SREBP-2 regulates the genes of cholesterol metabolism. [6] SREB proteins are indirectly required for …
SREBF1 Gene - GeneCards | SRBP1 Protein | SRBP1 Antibody
2024年12月25日 · SREBF1 (Sterol Regulatory Element Binding Transcription Factor 1) is a Protein Coding gene. Diseases associated with SREBF1 include Ifap Syndrome 2 and …
Sterol regulatory element-binding protein 1（SREBP1）
SREBP1（固醇调节元件结合蛋白1）是调控脂合成的重要转录调控因子，其合成后以非活性前体的形式存在于内质网。 当固醇浓度低时，SREBP1以依赖于COPII的方式从内质网转运到高尔 …
该文总结了受SREBP-1调控表达的靶基 因的特点, 着重介绍了胰岛素等上游因子在SREBP-1调控过程中的作用, 为指导治疗各类代谢性疾 病提供新的思路。 关键词 SREBP-1; 胰岛素; 靶基因; …
SREBP-1 是增加肝脏脂肪酸和甘油三酯合成的主要转录因子,本文回顾了近年来以SREBP-1相关通路为靶点NAFLD的研究进展。 Nonalcoholic fatty liver disease (NAFLD), one of the most …
Sterol regulatory element binding protein 1 couples …
2019年3月22日 · In this work, we identified acto-myosin contractility and mechanical forces imposed by the extracellular matrix (ECM) as SREBP1 regulators. SREBP1 control by …
SREBPs in Lipid Metabolism, Insulin Signaling, and Beyond
SREBPs are a family of membrane-bound transcription factors that activate genes encoding enzymes required for synthesis of cholesterol and unsaturated fatty acids. SREBPs are …
SREBP-1, a basic-helix-loop-helix-leucine zipper protein that …
We report the cDNA cloning of human SREBP-1, a protein that binds SRE-1, activates transcription, and thereby mediate the final regulatory step in LDL metabolism. SREBP-1 …