2019年6月18日 · Lymphatic endothelial cells (LECs) were the main source of CSF-1 within the lymph node and conditional deletion of Csf1 in adult LECs decreased the network of SSMs …

2019年6月18日 · Temporally controlled RANK removal in lymphatic endothelial cells (LECs) revealed that lymphatic RANK activation during embryogenesis and shortly after birth was …

In lymph nodes, subcapsular sinus macrophages (SSMs) form an immunological barrier that monitors lymph drained from peripheral tissues. Upon infec-tion, SSMs activate B and natural …

2024年10月1日 · These leukocytes are interspersed within the lymphatic endothelial cells (LEC) structuring the cortex of the subcapsular sinus. Both SSMs and LECs constitute the sorting …

2019年4月1日 · In lymph nodes, subcapsular sinus macrophages (SSMs) form an immunological barrier that monitors lymph drained from peripheral tissues. Upon infection, SSMs activate B …

In lymph nodes, subcapsular sinus macrophages (SSMs) form an immunological barrier that monitors lymph drained from peripheral tissues. Upon infection, SSMs activate B and natural …

2013年1月1日 · SSMs are extraordinary in terms of their transcellular position between LECs, with the head portion residing in the lymphatic lumen, the long “tail” extended into the B cell follicle …

First, SSMs required direct RANK signaling; second, both subsets relied on RANK-activated LECs. By silencing RANK expression in the SM compartment using Cd169-cre mice, we …

2019年6月18日 · CSF-1 that is secreted by both ceiling lymphatic endothelial cells (cLECs) and floor LECs (fLECs) provides a key cue for SSM differentiation and self-renewal. SSMs are …

2019年6月18日 · CSF-1 that is secreted by both ceiling lymphatic endothelial cells (cLECs) and floor LECs (fLECs) provides a key cue for SSM differentiation and self-renewal. SSMs are …