
STIM2 - Wikipedia
STIM2 protein is a type I transmembrane protein located in the S/ER. Human STIM2 consists of 833 amino acid residues (aas) (105-115 kDa) (Fig. 1), 148 additional aas compared to human …
STIM2 Gene - GeneCards | STIM2 Protein | STIM2 Antibody
2024年12月25日 · STIM2 (Stromal Interaction Molecule 2) is a Protein Coding gene. Diseases associated with STIM2 include T Cell And Nk Cell Immunodeficiency and Immunodeficiency …
STIM proteins: dynamic calcium signal transducers - Nature
2012年8月23日 · Stromal interaction molecule (STIM) proteins function in cells as dynamic coordinators of cellular calcium (Ca 2+) signals. Spanning the endoplasmic reticulum (ER) …
Role of STIM2 in cell function and physiopathology - PMC
An endoplasmic reticulum (ER)‐resident protein that regulates cytosolic and ER free‐Ca2+ concentration by induction of store‐operated calcium entry: that is the original definition of …
基质相互作用分子 2(STIM2)基因 | MCE - MCE-生物活性 ...
编码的蛋白质的功能是调节细胞质和内质网中的钙浓度,并参与质膜 Orai CA (2+) 进入通道的激活。 该基因从非 AUG (UUG) 起始位点开始翻译。 信号肽从产生的蛋白质上切下。 多个转录本 …
STIM2 stromal interaction molecule 2 [ (human)] - National …
2025年2月8日 · STIM2 is involved in spatial learning and plays an important role in ischemic-induced neuronal cell death during brain hypoxia. The absence of STIM2 reduces life …
New insights into the stromal interaction molecule 2 function and …
2024年9月13日 · STIM2 was reported closely correlated with the function of immune cells via regulating Ca2+ signaling, energy metabolism and cell fitness. Herein, we sum the latest …
北京师范大学揭示STIM蛋白激活的关键分子机制
最近的这个工作则进一步在SOAR区鉴定出了决定STIM结合Orai1能力强弱的关键位点(STIM1-G379/STIM2-E470),从而阐明了STIM特异性结合并激活Orai1的关键分子机制(PLOS …
A STIM2 splice variant negatively regulates store-operated
2015年4月21日 · Stromal interaction molecule (STIM) proteins regulate store-operated calcium entry (SOCE) by sensing Ca 2+ concentration in the ER and forming oligomers to trigger Ca …
Role of STIM2 in cell function and physiopathology - PubMed
2017年5月15日 · An endoplasmic reticulum (ER)-resident protein that regulates cytosolic and ER free-Ca 2+ concentration by induction of store-operated calcium entry: that is the original …