SALL4/ABCB6 Axis Suppresses Ferroptosis in Colon Cancer by
According to reports, the inhibition of ferroptosis is an essential culprit of malignant progression in various tumors, including colon cancer (CC). However, the relevant study on the regulatory …
USP37-stabilized SALL4 promotes the keloid formation by PI3K
2025年3月4日 · Spalt-like transcription factor 4 (SALL4) plays a vital role in the progression of many human diseases. However, the role and mechanism of SALL4 regulates in keloid …
Role of SALL4 in the progression and metastasis of colorectal cancer
2013年1月30日 · SALL4 is a zinc finger transcriptional activator crucial for maintenance of self-renewal in stem cells; however, its expression level has not yet been elucidated in colorectal …
The Invasion and Metastasis of Colon Adenocarcinoma (COAD) Induced by SALL4
2022年6月1日 · SALL4 Promoted EMT and Enhanced the Invasion of Colon Cancer Cells, while Silencing SALL4 Inhibited the EMT Phenotype and Reduced the Metastatic Potential of Colon …
The new advance of SALL4 in cancer: Function, regulation, and ...
2023年6月20日 · SALL4 regulates gastric cancer cell proliferation, migration, and invasion by activating the TGF-β/SMAD signaling pathway. SALL4 binds to the promoter region of the …
SALL4 advances the proliferation and tumor cell stemness of colon ...
2023年9月3日 · SALL4 is a transcription factor highly expressed in diverse cancers and is implicated in the development of cancer. SALL4 has been implied to play a cancer-promoting …
SALL4 EXPRESSION IN GERM CELL AND NON GERM-CELL …
SALL4 was only rarely (≤5%) expressed in mammary, colorectal, prostatic, and squamous cell carcinomas. Many SALL4 positive carcinomas showed poorly differentiated patterns and some …
The Invasion and Metastasis of Colon Adenocarcinoma (COAD) Induced by SALL4
2022年6月1日 · SALL4 played a vital role in tumor proliferation, invasion, and tumor EMT and may be a novel target for COAD. To sum up, TNM grading, histological grading, and lymphatic …
(a) SALL4 promoted the growth of SW480 cells, while the silenced SALL4…
Objective: The development and progression of many cancers may be related to SALL4, the role and molecular mechanism of which are unclear in colon adenocarcinoma (COAD). Methods: …
The new advance of SALL4 in cancer: Function, regulation, and ...
SALL4 is a stemness marker that regulates pluripotency and sustains the self‐renewal properties of ESCs and HSCs. In human adult tissue, its aberrant expression promotes cancer …
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