2016年3月2日 · We established the lentiviral system expressing short hairpin RNA to knockdown SALL4 in MCF-7/ADR cells. Down-regulation of SALL4 inhibited the proliferation of MCF …

Silencing SALL4 significantly reduces MCF‐7 cell migration, indicating that PEI25G10C50 is an effective gene‐delivery system for targeting SALL4 in breast cancer. 162. 7. CONCLUSION …

[Purpose] To investigate the effect of SALL4 gene silencing on the cellular proliferation and sensitivity of human breast cancer cell line MCF-7/A to chemotherapy. [Methods] The m RNA …

In this study, polycationic aminoglycoside-conjugated carboxyalkylated-PEI was used as a non-viral vector to deliver siRNA-SALL4 into MCF-7 cells. Megalin was exploited as one of the …

2018年4月4日 · To analyze the effect of SALL4 overexpression in a low-migratory luminal breast cancer cell line, MCF-7, we introduced the K190R mutation in full-length SALL4B-EGFP probe …

中国肿瘤016年第5卷第期ChinaCancer016Vol.5No.SALL4基因沉默对MCF-7/A细胞增殖和化疗敏感性的影响收稿日期：015-10-10；修回日期：015-11-17基金项目：国家自然科学基 …

SALL4 gene encodes a transcription factor and is overexpressed in some cancers. Methods: In this study, carboxyalkylated-PEI25 (25 kDa) was used to deliver plasmids expressing SALL4 …

Down-regulation of SALL4 inhibited the proliferation of MCF-7/ADR cells and induced the G1 phase arrest in cell cycle . In line with these findings, we demonstrated that down-regulating …

In this study, we have evaluated the implication of SALL4 in the HER2+ subtype through its expression in patients’ samples and gain and loss of function in HER2+ cell lines. We found …

2018年4月27日 · In this study, we observed that treating MCF-7 and SUM159 breast cancer cell lines with a proteasome inhibitor increases SALL4 protein levels, suggesting that SALL4 is …