The SCOP database, created by manual inspection and abetted by a battery of automated methods, aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between all proteins whose structure is known.

SCOPe (Structural Classification of Proteins — extended) is a database developed at the Berkeley Lab and UC Berkeley to extend the development and maintenance of SCOP. SCOP was conceived at the MRC Laboratory of Molecular Biology, and developed in collaboration with researchers in Berkeley.

The Structural Classification of Proteins (SCOP) database is a largely manual classification of protein structural domains based on similarities of their structures and amino acid sequences. A motivation for this classification is to determine the evolutionary relationship between proteins.

The meaning of SCOP is an Old English bard or poet.

The SCOP database aims to provide a detailed and comprehensive description of the structural and evolutionary relationships between proteins whose three-dimensional structure is known and deposited in the Protein Data Bank. The main levels of the classification are:

A scop (/ ʃ ɒ p / [1] or / s k ɒ p / [2]) was a poet as represented in Old English poetry.The scop is the Old English counterpart of the Old Norse skald, with the important difference that "skald" was applied to historical persons, and scop is used, for the most part, to designate oral poets within Old English literature. Very little is known about scops, and their historical existence is ...

Structural Classification of Proteins — extended (SCOPe) is a database of protein structural relationships that extends the SCOP database. SCOP is a (mostly) manually curated ordering of domains from the majority of proteins of known structure in a hierarchy according to structural and evolutionary relationships.

SCOPe is a database developed at the Berkeley Lab and UC Berkeley that extends SCOP (version 1). SCOPe classifies many structures released since SCOP 1.75 through a combination of automation and manual curation, and corrects some errors, aiming to have the same accuracy as the fully hand-curated SCOP releases.

2024年6月25日 · What is SCOP and SCOP-e? The Structural Classification of Proteins (SCOP) database was created in the 1990s by mostly manual inspection and by ordering domains of known protein structures according to a hierarchy based on structural and evolutionary relationships (Murzin et al., 1995).

2024年6月25日 · Protein type groups together folds and IUPRs into four groups: soluble, membrane, fibrous and intrinsically disordered. Each of these types correlate with characteristic sequence and structural features. The SCOP database classifies non-redundant protein domains.