仙台病毒 - 维基百科，自由的百科全书
仙台病毒 （Sendai virus，簡稱 SeV）又稱 鼠呼吸道病毒 （murine respirovirus）、 鼠副流感病毒一型 （murine parainfluenza virus type 1）與 日本凝血性病毒 （hemagglutinating virus of Japan，HVJ），為 副黏液病毒科 呼吸道病毒屬 的一種病毒 [2][3]，屬 負鏈單股RNA病毒 （英语 ...
Murine respirovirus - Wikipedia
Murine respirovirus, formerly Sendai virus (SeV) and previously also known as murine parainfluenza virus type 1 or hemagglutinating virus of Japan (HVJ), is an enveloped, 150-200 nm–diameter, negative sense, single-stranded RNA virus of the family Paramyxoviridae. [2][3][4] It typically infects rodents and it is not pathogenic for humans or ...
什么是仙台病毒？ - 知乎专栏
仙台病毒 (Sendai virus,SeV )属于 副粘病毒科， 副黏病毒属，有囊膜，是一个有血凝性和细胞融合性的呼吸道病毒，是带包膜的单股负链RNA病毒，基因组全长约15kb，主要感染啮齿类动物，引起动物的呼吸系统类疾病。
最著名的反义RNA病毒——仙台病毒 - 哔哩哔哩
鼠呼吸道病毒 (Murine Respirovirus)，以前称为仙台病毒 (SeV)、鼠副流感病毒1型或日本血凝病毒 (HVJ)，是一种有包膜、直径为150-200nm、反义的单链RNA病毒。 它通常感染啮齿动物，对人类或家畜没有致病性。 仙台病毒 (SeV) 是呼吸道病毒家族 (Respirovirus)的成员。 该病毒于1950年代初在日本仙台市被分离出来。 从那时起，它作为模型病原体被积极用于研究。 该病毒对许多癌细胞系具有传染性，在动物模型和动物自然发生的癌症中具有溶瘤特性。 SeV融合真核细胞和形 …
Development of Sendai Virus Vectors and their Potential Applications …
The Sendai virus (SeV) vector is a newcomer in the field with unique characteristics, making it distinct from other viral vectors. In this review, we introduce characteristics of various SeV vectors, a unique RNA virus-based gene delivery/expression system and describe recent progress in the application of SeV vectors to molecular therapy and ...
Safety and immunogenicity of an intranasal sendai virus-based …
2021年2月1日 · SeVRSV is a replication-competent Sendai virus (SeV)-based vaccine carrying the respiratory syncytial virus (RSV) fusion protein (F) gene. Unmanipulated, non-recombinant SeV is a murine parainfluenza virus type 1 (PIV-1) and …
Sendai Virus Targets Inflammatory Responses, as Well as the …
Our results suggest that SeV targets the inflammatory and adaptive immune responses as well as the IFN-induced intracellular antiviral state by using a multifaceted approach. Alpha/beta interferons (IFN-α/β) are cytokines that act in a pleiotropic manner to …
Sendai virus for gene therapy and vaccination - PubMed
Sendai virus (SeV), also known as hemagglutinating virus of Japan (HVJ), is a negative-strand RNA virus and a member of the paramyxovirus family. The capacity of SeV to enhance fusion of lipid vesicles and cell membranes was recognized in the early 1980s, and has since been utilized in the form of H …
Quantification of Infectious Sendai Virus Using Plaque Assay
2018年11月5日 · Sendai virus (SeV) is an enveloped, single-stranded RNA virus of the family Paramyxoviridae. SeV is a useful tool to study its infectious pathomechanism in immunology and the pathomechanism of a murine model of IgA nephropathy.
Safety and immunogenicity of an intranasal sendai virus-based …
SeVRSV is a replication-competent Sendai virus (SeV)-based vaccine carrying the respiratory syncytial virus (RSV) fusion protein (F) gene. Unmanipulated, non-recombinant SeV is a murine parainfluenza virus type 1 (PIV-1) and serves as a Jennerian ...