SLC44A4 Gene - GeneCards | CTL4 Protein | CTL4 Antibody
2024年12月25日 · SLC44A4 (Solute Carrier Family 44 Member 4) is a Protein Coding gene. Diseases associated with SLC44A4 include Deafness, Autosomal Dominant 72 and Rare …
ADC征战前列腺癌-新旧靶点临床结果几何？ - 梅斯医学 ...
2022年10月13日 · ihc 研究显示 slc44a4 在几种肿瘤中的表达上调，包括 85% 的原发性 pca。在分化较差的肿瘤中证明了其较高的表达。体内研究揭示了 slc44a4 定向抗体在雄激素依赖性和非 …
Choline transporter-like protein 4 - Wikipedia
Choline transporter-like protein 4 is a protein that in humans is encoded by the SLC44A4 gene. [5] [6] [7]
The Discovery and Preclinical Development of ASG-5ME, an …
2016年11月1日 · Here, we describe the expression of SLC44A4 in pancreatic and prostate cancers and report on the preclinical development of ASG-5ME, an ADC composed of an …
SLC44A4- 信号通路|蛋白抗体-华美生物
slc44a4，即溶质载体家族44成员4，别名ctl4、ng22、tppt、dfna72、htppt1、c6orf29。它是一种由人类slc44a4基因编码的跨膜蛋白，属于slc44家族。slc44a4在多种组织中表达，尤其在结 …
A phase 1 clinical trial of ASG-5ME, a novel drug-antibody
Purpose ASG-5ME is an antibody-drug conjugate (ADC) targeting SLC44A4, a novel cell surface target expressed on most pancreatic and gastric cancers. This first-in-human study of ASG …
SLC44A4 solute carrier family 44 member 4 [ (human)]
2025年2月8日 · Whole-exome sequencing revealed SLC44A4, which encodes the choline transport protein, as the pathogenic gene in this family. In the zebrafish model, downregulation …
溶质载体家族 44 成员 4（SLC44A4）基因 | MCE
该基因编码的蛋白质可能是一种钠依赖性跨膜转运蛋白，参与胆碱能神经元对胆碱的摄取。 该基因的缺陷会导致唾液酸贮积症，这是一种溶酶体贮积病。 已发现该基因的三个转录变体编码不 …
The choline transporter-like family SLC44: Properties and roles …
SLC44A1 is widely expressed throughout the nervous system in both neurons and oligodendrocytes, while SLC44A2-4 are mainly detected in peripheral tissues. The subcellular …
A phase I study of the antibody drug conjugate ASG-5ME, an SLC44A4 …
ASG-5ME, an SLC44A4-targeting antibody carrying monomethyl auristatin E (MMAE), a microtubule-disrupting agent, was investigated in men with metastatic castration resistant …
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