经典信号通路总结——TGF-β信号通路 - 知乎 - 知乎专栏
Smad（由线虫的Sma和果蝇的Mad缩写而来）蛋白是TGF-β家族受体下游的信号转导分子。在哺乳动物中总共存在八个Smad蛋白（Smad1到Smad8）。 根据在TGF-β信号转导中的功能差 …
SMAD (protein) - Wikipedia
The human homologue of Mad and Sma was named Smad1, a portmanteau of the previously discovered genes. When injected into Xenopus embryo animal caps, Smad1 was found to be …
SMAD1 Gene - GeneCards | SMAD1 Protein | SMAD1 Antibody
2024年12月25日 · SMAD1 (SMAD Family Member 1) is a Protein Coding gene. Diseases associated with SMAD1 include Juvenile Polyposis/Hereditary Hemorrhagic Telangiectasia …
TGF-β信号通路与Smad家族蛋白 - 纽普生物
Smad蛋白（Smad是由线虫的Sma和果蝇的Mad缩写而来） 是TGF-β家族受体下游的信号转导分子[1,2]。在哺乳动物中有八个Smad蛋白, Smad1、 Smad1、 ...、 Smad8。 根据在TGF-β信号 …
Smad蛋白 - 百度百科
Smads家族蛋白在将 TGF -β信号从 细胞表面受体 传导至 细胞核 的过程中起到关键性作用，且不同的Smad介导不同的TGF-β家族成员的信号转导。 TGF-β作为 配体 形成的受体复合物，激 …
Mothers against decapentaplegic homolog 1 - Wikipedia
Mothers against decapentaplegic homolog 1 also known as SMAD family member 1 or SMAD1 is a protein that in humans is encoded by the SMAD1 gene. [4][5] SMAD1 belongs to the SMAD, …
SMAD1 as a biomarker and potential therapeutic target in …
2021年6月16日 · This study identifies SMAD1 regulation of NF-κB1/TNFAIP8 and ID1-p21/p27 as critical axes of MM drug resistance and provides a potentially new therapeutic strategy to treat …
SMAD1 SMAD family member 1 [ (human)] - National Center for ...
SMAD1 signaling may be a key pathway contributing the pathogenesis of Cardio-facio-cutaneous syndrome during early development. Smad1 elevation serves as a compensatory mechanism …
SMAD Proteins in TGF-β Signalling Pathway in Cancer: Regulatory ...
The expression levels of SMAD proteins have an important impact on the tumour microenvironment and therapeutic efficacy. Studies have shown that SMAD1 is highly …
Smad1 Promotes Tumorigenicity and Chemoresistance of …
2024年12月4日 · Smad1 forms a complex with p53 and p300, inhibiting p300's interaction with p53 and leading to reduced p53 acetylation and increased Smad1 acetylation in GBM. This …