SMC6 Gene - GeneCards | SMC6 Protein | SMC6 Antibody
Dec 25, 2024 · SMC6 (Structural Maintenance Of Chromosomes 6) is a Protein Coding gene. Diseases associated with SMC6 include Fanconi Anemia, Complementation Group F and …
SMC6 - Wikipedia
Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene. [5][6] The SMC6 was discovered first in fission yeast as RAD18 (SMC6).
染色体结构维持蛋白Smc5/6复合体的结构与功能
Jun 1, 2021 · Smc5/6复合体在真核生物中分布广泛且高度保守，在DNA损伤同源重组修复、DNA复制、端粒长度维持及胚胎发育中发挥重要作用。 本文系统介绍了Smc5/6复合体结构特 …
揭示染色体结构维持复合物-Smc5/6的组装及调控机制 - 基因频道
Jun 20, 2024 · Smc5/6已进化出多种功能来调节基因组复制、DNA损伤修复和一系列病毒的外体DNA，如乙型肝炎病毒、 人类免疫缺陷病毒 和人类乳头瘤病毒。 Smc5/6如何在染色体和表 …
Cryo-EM structures of Smc5/6 in multiple states reveal its …
Jun 18, 2024 · Here, we report cryo-EM structures of the budding yeast Smc5/6 complex in eight-subunit, six-subunit and five-subunit states. Structural maps throughout the entire length of …
PNAS | SMC5/6复合体结构全景分析
SMC蛋白复合物（Structural maintenance of chromosomes complex）是一类高度保守的具有ATP酶活性的多亚基复合物，对染色体的结构维持、DNA复制以及转录调控等均具有重要的作 …
DNA segment capture by Smc5/6 holocomplexes | Nature …
Apr 3, 2023 · Among the SMC complexes, Smc5/6 has dedicated roles in DNA repair and preventing a buildup of aberrant DNA junctions. In the present study, we describe the …
The multi-functional Smc5/6 complex in genome protection and
Jun 19, 2023 · Among the three types of SMC complexes in eukaryotes, cohesin and condensin fold the genome into different domains and structures, while Smc5/6 plays direct roles in …
DNA-binding properties of Smc6, a core component of the …
Dec 9, 2011 · We report the first biochemical characterization of purified full-length Smc6. Smc6 is an ATP-regulated and conformation-sensitive DNA-binding protein. Smc6 has a clear …
研究揭示染色体结构维持复合物-Smc5/6的组装及调控机制----中国 …
Jun 19, 2024 · Smc5/6复合物由Smc5、Smc6和六个非SMC元件（Nse1-6）8个亚基组成，但完整Smc5/6复合物的结构信息的缺失阻碍了对其多元化生物学功能的研究。 该团队利用杆状病毒 …