Synaptonemal complex protein 3 is a protein that in humans is encoded by the SYCP3 gene. [5][6][7] It is a component of the synaptonemal complex formed between homologous …

2024年12月25日 · SYCP3 (Synaptonemal Complex Protein 3) is a Protein Coding gene. Diseases associated with SYCP3 include Spermatogenic Failure 4 and Male Infertility. Among its related …

2020年6月26日 · In mammals, eight SC protein components have been identified so far: the proteins SYCP2 and SYCP3 of the lateral elements, SYCP1 of transverse filaments and the …

2025年2月8日 · SCP3 is associated with lymphangiogenesis and provides insight into the SCP3-VEGF-C/VEGF-D axis based cancer therapy strategy. In the model, the reported compaction …

2001年4月16日 · SYCP3 localizes to the lateral elements of the synaptonemal complex and is essential for male meiosis. The genomic structure of SYCP3 consists of nine exons spanning …

Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same …

Here we show that human SYCP3 forms a highly-elongated helical tetramer of 20 nm length. N-terminal sequences extending from each end of the rod-like structure bind double-stranded …

2014年6月20日 · A structural and biochemical study of human SYCP3 provides the first molecular model for the three-dimensional organisation that is imposed upon chromosomal DNA during …

2024年12月24日 · SYCP3，全称synaptonemal complex protein 3，是一个位于人类染色体12q23.2的基因。它的主要功能是编码一种蛋白质，这种蛋白质在细胞的减数分裂过程中起着 …

2019年10月31日 · Interaction between SYCP3 molecules is driven by the intrinsically disordered tails of the protein, with no contact between the helical cores, resulting in a flexible fibre …