2024年11月30日 · The ECG is a vital tool in the prompt diagnosis of poisoning with sodium-channel blocking medications such as tricyclic antidepressants (TCA), which cause CNS and …

Inhibition of presynaptic neurotransmitter reuptake (norepinephrine and serotonin) is the primary mechanism for the therapeutic effects of tricyclic antidepressants (TCAs). Following overdose, …

Pre-intubation and on arrival it is vital to get an ECG looking for signs of toxicity (widening of the QRS, large terminal R wave in aVR increased R/S ratio (>0.7) in aVR and QT prolongation).

2009年9月26日 · Discuss the classic EKG findings of tricyclic antidepressant cardiotoxicity (TCA). Formulate an empiric treatment regimen based on EKG findings. Summarize the relevance of …

2021年4月26日 · Tricyclic antidepressants (TCAs) are the perhaps the most widely discussed intoxicant which inhibits sodium channels (causing a characteristic pattern of QRS widening …

2018年3月22日 · What are the main ECG pointers for TCA overdose? Cardiac toxicity can develop quickly in TCA overdose, so get an ECG early in the clinical course if suspecting the …

2022年5月7日 · 12-lead ECG: TCA toxicity causes serious and potentially fatal arrhythmias. Typical ECG findings include widened QRS and prolonged QTc (Figure 1). Patients with an …

2008年1月24日 · Patients presenting TCA overdose should be treated with great care and a high index of suspicion, particularly if the symptoms are progressive. Challenging EKG and 12-lead …

2024年12月18日 · A QRS duration >100 ms suggests blockade of cardiac fast sodium channels. In combination with right axis deviation of the terminal QRS, it is virtually pathognomonic (see …

This document discusses the electrocardiogram (EKG) findings associated with tricyclic antidepressant (TCA) toxicity. It notes that TCAs can cause: 1) Sodium channel blockade …